Immuno13 Flashcards
Therapeutic Antibodies
1
Q
Muromonab-CD3 (OKT3)
A
Target: CD3
Use:
- Prevent acute Transplant rejection
2
Q
Digoxin Immune Fab
A
Target: Digoxin
Use:
- Antitode for digoxin intoxication
3
Q
Infliximab
A
Target: TNF-a Use: - Crohn's disease - Rheumatoid arthritis - Psoriatic arthritis - Ankylosing spondylitis
4
Q
Adalimumab
A
Target: TNF-a Use: - Crohn's disease - Rheumatoid arthritis - Psoriatic arthritis
5
Q
Abciximab
A
Target: Glycoprotein IIb/IIIa
Use:
- Prevent cardiac ischemia in unstable angina
- Patients with Percutaneous Coronary intercention
6
Q
Trastuxumab
A
Target: HER2
Use:
- HER2-overexpressing Breast Cancer
7
Q
Rituximab
A
Target: CD20
Use:
- B-cell Non-Hodgkin’s lymphoma
8
Q
Omalizumab
A
Target: IgE
Use:
- Additional line of treatment for Severe Asthma
9
Q
Daclizumab
A
Target: IL-2 receptor
Use:
- Severe Combined Immunodificiency disorder (SCID)