Immunizations Flashcards
How much time must elapse before giving a live vaccine to a patient who received a product containing antibodies
wait 3 months or longer before giving vaccine - MMR and varicella containing vaccine (except zoster) consult pink book for blood product/vaccine timeline
How much time must elapse before giving antibody containing products after a live vaccine is given
wait 2 weeks before giving antibody
Which vaccines( polysaccharide or conjugate) do not consistently produce an effective immune response in children under 2
polysaccharide
Live vaccines are withheld until what age
12 months of age - due to mother’s antibodies
Age at which inactivated vaccines can be started and exception
2 months (except Hepatitis B - at birth)
Which diseases is simultaneous administration of antibody and vaccine recommended as post exposure prophylaxis
hepatitis A, hepatitis B, rabies, tetanus
Which vaccines shouldn’t be administered simultaneously?
PCV 13 and Menactra (meningococcal conjugate) - seperated by at least 4 weeks
If live vaccines are not given together, how far should they be seperated?
at least 4 weeks
Which vaccines are Live vaccines
MMR, MMRV, varicella, zoster, yellow fever, LAIV
Effect of increasing the dosing interval in a vaccination series
delayed protection - no decrease in effectiveness
effect of decreasing the dosing interval in a vaccination series
may decrease effectiveness
Live vaccines and PPD timeline
give on the same day or if vaccine given first wait 4 weeks before placing PPD, if PPD given first wait until after reading to give vaccine
Most common vaccine adverse reactions
local reactions - pain, sweling, and redness of injection site - up to 80%, most common with inactive vaccines
Systemic adverse reactions to vaccines
fever, malaise, myalgias, headache, loss of appetite, mild manifestations of the disease being protected against, - mild and occurring within 7-21 days of the vaccine
Are minor allergic reactions a contraindication to repeat vaccination
no
When do anaphylactic allergies occur after a vaccine (timeframe)
minutes to hours
S/s of anaphylactic reaction
urticaria, swelling of the mouth and throat, difficulty breathing, wheezing, abdominal cramping, hypotension, shock
Amount of corticosteroids to get systemic steroid induced immunosuppression
20+ mg/day prednisone x 14+ days, 2+mg/kg/day prednisone x 14+ days
Contraindications to live vaccines
pregnancy, immunosuppression
How long after chemotherapy to be able to give live vaccines
at least 3 months after discontinuation of chemo
Which vaccines are contraindicated in HIV with a CD4 count
MMR, Varicella
Asplenic patients should received which vaccines
PCV13 AND PPSV23. can receive live vaccines if indicated
optimum time for Tdap vaccination during pregnancy
27 and 36 weeks
Which vaccines are recommended for health care professionals
Hepatitis B, Flu, MMR, Varicella, Tdap
DTaP brand names
Daptacel, Infanrix
DTaP-IPV brand name
Kinrix
DTaP - HepB-IPV brand name
Pediarix
DTaP-IPV/Hib brand name
Pentacel
DTap series given to who
children
DTaP dosing
5 doses at age 2, 4, 6, 12-18 months and 4-6 years. followed by Tdap at 11-12 years
Hib vaccine brand names
ActHIB, Hiberix, PedvaxHIB
MenCY-Hib vaccine brand names
Menhibrix (Meningococcal serogroups C and Y - Hib)
When is Hib vaccination given
children, sometimes adults after splenectomy Menhibrix - high risk infants 6 weeks - 18 months
Hep A vaccine brand names
Havrix, Vaqta
Hep B vaccine brand names
Engerix B, Recombivax HB
Hep A / Hep B vaccine brand name
Twinrix
Who gets Hep A vaccination
children at 1 year of age (2 doses); adults: men who have sex with men, IVDU, chronic disease, travelers to countries with high incidence