Immunization Flashcards
Examples of live attenuated vaccines
MMRV, rotavirus, oral polio, BCG, oral typhoid
If a live vaccine is given first, it is necessary to wait __ before giving an antibody
2 weeks
Interval between hepatitis A/B prophylaxis and live vaccine
3 months
Interval between standard measles prophylaxis and live vaccine is __; for immunocompromised __
standard - 5 months
immunocompromised - 6 months
Interval between rabies prophylaxis and live vaccine
4 months
Interval between tetanus prophylaxis and live vaccine
3 months
Interval between IVIG and live vaccine for:
- replacement therapy of immune deficiencies
- ITP 400 mg/kg
- ITP 1000 mg/kg
- varicella postexposure prophylaxis
- Kawasaki disease
- Immune deficiency - 8 months
- ITP 400 - 8 months
- ITP 1000 - 10 months
- varicella - 8 months
- Kawasaki - 11 months
Interval between washed pRBC and live vaccine
none
Interval between pRBC and live vaccine
6 months
Interval between whole blood and live vaccine
6 months
Interval between plasma or platelet products and live vaccine
7 months
Examples of inactivated whole-cell viral vaccines
polio, hepatitis A, rabies
Examples of inactivated whole-cell bacterial vaccines
pertussis, cholera
Examples of fractional vaccine subunits
hepatitis B, influenza, acellular pertussis, HPV
Examples of fractional vaccine toxoids
diphtheria, tetanus
Examples of pure polysaccharide vaccines
pneumococcal, meningococcal, typhoid
Examples of conjugated polysaccharide vaccines
HiB, pneumococcal, meningococcal
Examples of inactivated, genetically engineered recombinant vaccines
hep B, HPV
Two exceptions to no interval between inactivated vaccine administration and simultaneous vaccine administration:
- Tdap and MCV4 (at least 4 weeks if not simultaneous)
2. yellow fever vaccine and cholera vaccine (at least 3 weeks)
2 permanent contraindications to further doses of a vaccine
- severe anaphylactic reaction
2. encephalopathy not due to another identifiable cause occurring within 7 days of a pertussis vaccination
Two conditions that are temporary contraindications to live vaccines
- pregnancy
- immunosuppression
- asymptomatic HIV may receive live vaccines
A history of GBS is a precaution for which vaccines
tetanus-containing
influenza
meningococcal conjugate
Permanent precautions to further doses of pediatric pertussis-containing vaccine when occurring within 48 hours of a dose
- Temperature 40.5 C or higher
- Hypotonic, hyporesponsive episode
- Persistent inconsolable crying for 3 hr
- Seizure with or without fever within 3 days
Two conditions that are temporary precautions to administering measles- and varicella-containing vaccines
- Moderate or severe acute illness
2. Recent administration of an antibody-containing blood product
Children aged __ should receive pediatric dose of diphtheria vaccine
younger than 7 yr
Schedule of primary series of diphtheria vaccine and booster dose
primary series: 6-10-14 w and 12 mo
(4th dose should follow 3rd dose by no less than 6 months and not before 12 mo)
(give a 5th dose if 4th dose is given before 4 yr)
booster at 4-6 yr and every 10 yr
Schedule of diphtheria vaccination in 7 yr and older
primary series: Td 3 doses, first 2 are 4 weeks apart, 3rd dose is 6-12 mo from 2nd dose
Recommended interval between Tdap and Td
5 yr
Minimum interval between MRRV doses
3 mo
MRRV is approved for what ages?
12 mo-12 yr
Infants 6 w-6 mo should receive __ doses of HiB vaccine administered __ apart, followed by a booster dose at __ give at least __ months after the last dose.
3 doses
1-2 months apart
Booster at 12-15 mo
2 months after last dose
Unvaccinated infants 7-11 mo should receive __ doses of HiB vaccine administered __ apart followed by a booster dose at __ given at least __ from the last dose
2 doses
1-2 months apart
Booster at 12-15 months
At least 2 months from last dose
Unvaccinated children aged 12-14 mo should receive __ doses of HiB vaccine __ apart.
2 doses
1-2 months apart
Previously unvaccinated children aged 15-59 mo should receive how many doses of HiB vaccine?
1 dose
Infants born to HBsAg positive mothers should receive first dose of Hep B vaccine within __ after birth and the last dose by __.
First within 12 hr
Last by 6 mo
For infants of HBsAg mothers should be tested for HBsAg and anti-HBs at __ to monitor success of therapy
9-18 mo
Maximum age for rotavirus vaccine
8 mo
Which rotavirus vaccine can be given to patients with latex allergy?
Pentavalent rotavirus
Vaccine that cannot be given to people with history of egg anaphylaxis
Influenza vaccine