Immunity Against Microbe

Question 1

Innate immunity
Microbe: IC bacteria
Phagocytes : 1st _____ then ______
NK : produce _____ to + ______
Kill VlC with absence of _____
Type 1 lFN :
Complement:

Answer 1

Neutrophils, MQ
IFN Gama (type 2 interferon) , MQ&DC
MHC1
No function
No function

Question 2

Innate
Microbe : viruses
Phagocytes: ____
NK :kill ____ due to _____
Type 1 IFN:
1. released from ____ to prevent virus replication in ____&____ , this is called _____
2. Enhance killing of ____ by increasing _____ on infected cells
And increasing of ______ or _______ of NK and CTLs
Complement:

Answer 2

No function
VIC , absence of MHC1
Infected cell , non-infective , infective , antiviral state
VIC, MHC1 , cytotoxicity, activation
No function

Question 3

Innate
Microbe : EC bacteria الغالبية الساحقة
Phagocytes:
1.MQ and DC recognize EC bacteria by ______ and ______ like ____
Phagocytes kill and digest ingested bacteria by _______
2.Phagocytes secrete ________to recruit ______
Nk: ___

Type 1 lFN : _____

Complement: Complement activation:ECB + ______&_____ pathway

Answer 3

PRR, opsonin receptor , c3bR
Lysozome
Inflammatory cytokines, leucocytes
No function
No function
Alternative, lectin

Question 4

Type 1lFN cause antiviral state, name them

Answer 4

A. Decrease protein synthesis
B. Degradation(تكسير) of viral RNA
C. Inhibit viral gene expression and assembly

Question 5

CMI : main ____ or eradicates _____

Adaptive

Microbe : IC bacteria

1. Th : Th 1 produce _____ to + __
   to kill ICB by _____.
   Th is + by peptide Age (____) from ________ or phagolysosome
2. CTLs : kill _____ expressing _______

Answer 5

Main protective immunity
Eradicates establised infection
IFN Gama
MQ
Phagosomes
MHC2
Intravesicular bacteria
Infected cells
Bacteria Ag associated MHC1

Question 6

Adaptive
Microbe : viruses
# CMI : main _______
1.Th : no function
2.CTL: kill ___ expressing ______

Answer 6

Main protective immunity
VIC , foreign Ag associated MHC1

Question 7

Adaptive
# CMI : not main protective immunity
Microbe : EC BACTERIA

1. A)Th1 produce ____ to + ____&____
   B) Th17 produce _____ to recruit neutrophils and MQ creating ______

C) Th2 produce _____ ,______ and ____ to + B cell ______ and ______

2. CTL :_____

Answer 7

IFN gamma
MQ , neutrophils
IL-17
Local inflammation لحست مخك 😂
IL4,lL5,IL13
Growth
Differentiate
No function