Immunity Flashcards
How is passive immunity acquired?
Pre-formed Abs
What is the onset of passive immunity?
Rapid
What is the duration of passive immunity?
Short Span of Abs (half life = 3wks)
Example of passive immunity
IgA in breast milk
Antitoxin
Humanized mAb
How is active immunity acquired?
Exposure to foreign Ags
What is the onset of active immunity?
Slow
What is the duration of active immunity?
Long lasting (memory)
Example of active immunity
Natural infection
Vaccines
Toxoid
What can be given in case of Hep B or Rabies exposure?
Combined passive and active immunizations
Which pathogens are you most susceptible post-splenectomy?
Strep pneumo Hib Neisseria meningitidis E. coli Salmonella Klebsiella pneumo Group B Strep
(SHiNE SKiS)
What pathogens are you most susceptible to if you have no granulocytes?
Staph
Serratia
Burkholderia cepacia
Nocardia