Autoantibodies Flashcards

1
Q

Anti-nuclear Abs (ANA)

A

SLE

Nonspecific

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2
Q

Anti-dsDNA, Anti-Smith

A

SLE

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3
Q

Anti-histone

A

Drug-induced Lupus

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4
Q

Rheumatoid Factor, Anti-CCP

A

Rheumatoid Arthritis

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5
Q

Anti-centromere

A

Scleroderma (CREST syndrome)

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6
Q

Anti-Scl-70 (DNA Topoisomerase I)

A

Scleroderma (diffuse)

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7
Q

Anti-mitochondrial

A

Primary Biliary Cirrhosis

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8
Q

IgA Anti-endomysial, IgA Anti-tissue Transglutaminase

A

Celiac disease

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9
Q

Anti-basement membrane

A

Goodpasture Syndrome

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10
Q

Anti-desmoglein

A

Pemphigus Vulgaris

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11
Q

Anti-microsomal, Anti-thyroglobulin

A

Hashimoto’s Thyroiditis

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12
Q

Anti-Jo-1, Anti-SRP, Anti-Mi-2

A

Polymyositis

Dermatomyositis

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13
Q

Anti-SSA (Anti-Ro)

Anti-SSB (Anti-La)

A

Sjogren’s Syndrome

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14
Q

Anti-U1 RNP (Ribonucleoprotein)

A

Mixed CT disease

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15
Q

Anti-Smooth Mm.

A

Autoimmune Hepatitis

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16
Q

Anti-Glutamate Decarboxylase

A

DM 1

17
Q

c-ANCA (PR3-ANCA)

A

Wegener’s (Granulomatosis with Polyangiitis)

18
Q

p-ANCA (MPO-ANCA)

A

Churg-Strauss

Microscopic Polyangiitis