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Patho > Immunity > Flashcards

Immunity Flashcards

1
Q

immune response

A

protection from disease

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2
Q

nonspecific responses

A

phagocytosis, inflammation

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3
Q

specific responses

A

production of specific antibodies against foreign substances

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4
Q

antigens - self

A

immune system ignores

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5
Q

antigens - nonself

A

immune system recognizes as foreign

development of a specific response to that antigen

memory cells produced to respond quickly to antigen

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6
Q

macrophages

A

everywhere in body

initiate immune response

engulf foreign material

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7
Q

chemicals secreted by macrophages

A

monotones, interleukins

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8
Q

T lymphocytes

A

from bone marrow stem cells

further differentiation in thymus

cell mediated immunity

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9
Q

cytotoxic T killer cells

A

kill antigen immediately

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10
Q

helper T cells

A

activate more response and cells

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11
Q

memory T cells

A

remember the antigen

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12
Q

B lymphocytes

A

mature in bone marrow

produce antibodies

humoral immunity

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13
Q

plasma cells

A

produce antibodies

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14
Q

B memory cells

A

can quickly form clone of plasma cells

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15
Q

humoral immunity

A

antibody proteins in blood

B lymphocytes

defense against EXTRAcellular

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16
Q

cell mediated immunity

A

phagocytic cells

T lymphocytes

defense against INTRAcellular

17
Q

IgG

A

most common in blood

antibacterial

crosses placenta

18
Q

IgM

A

bound to B lymphocytes

1st to increase in immune system

involved in ABO type incompatibility rxn

19
Q

IgA

A

in secretions

tears, saliva, mucous membranes, colostrum

20
Q

IgE

A

allergic response

bind to mast cells

releases histamine

inflammation

21
Q

IgD

A

attached to B cells

activates B cells

22
Q

chemical mediators

A

inflammation and immune responses

histamine, kinins, prostaglandins, leukotrienes, cytokines

23
Q

complement system

A

group of inactive proteins circulating in blood

causes cell damage and further inflammation

activated with IgG or IgM

24
Q

active natural immunity

A

direct exposure (infection)

antibodies are produced

25
Q

active artificial immunity

A

immunization

antigen introduced to body - stimulates antigen production

26
Q

passive natural immunity

A

breastfeeding

IgG transferred from mother to fetus

27
Q

passive artificial immunity

A

injection of antibodies

short term protection

28
Q

primary response

A

1st exposure to antigen

T lymphocytes and creation of B memory cells

29
Q

secondary response

A

repeat exposure to same antigen wit higher antibody response

B memory cells kick in for rapid response

vaccine boosters

30
Q
A

Patho (5 decks)

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