Immunity Flashcards
Natural immunity
(Innate)
Born with it
Skin, mucous membranes, NK cells, inflammation and phagocytosis
Phagocytes: Neutrophils, macrophage, dendritic
Antigen presenting cells: B cells, macrophage, dendritic
Does NOT involve exposure
3 Phagocyte cells
Neutrophils
Macrophage
Dendritic
3 antigen cells
B cells
Macrophage
Dendritic
Neutrophil
Present during acute inflammation
Eat microbes
Macrophage
Derived from Monocytes
Eat microbes
Differentiate In tissues
Dendritic cell
Eat antigens in skin, GI, and resp
Nk cells
Not specific
Weak sauce at their job
Kill virus and cancer
Acquired immunity
AFTER EXPOSURE
After birth
Improve with repeat exposure
Antigen exposure or vaccine
Passive acquired immunity
Acquired from transfer of antibody or T cell to recipient
Natural passive
Mother to baby and mother to fetus
Breast milk, placenta
Artificial passive immunity
Antibodies given to recipient to provide immunity
Treat rabies, tetanus, snek bite, hepatitis (but immunity only lasts 2 weeks)
Humoral immunity
B cell
Viral, toxin diseases, pneumococci, meningococci, haemophilius
Cell mediated immunity
T cell
Bacteria, virus, cancer, fungus, parasite, tumor
ORGAN TRANSPLANT REJECTION
Sickle cell anemia patients are at risk for _______ if they get spleen removed
Infection
- Particularly strep
- Need pneumococcal vaccine
IgG
Most abundant
Primary antibody in secondary immune response (newborn doesn’t have much yet)
Only one to cross placenta
