Immunisations Flashcards
Aim of vaccinations
control of communicable diseases.
3 immunological mechanisms
Active immunity
Passive immunity
Herd immunity
2 examples of passive immunity:
mother to unborn baby (via placenta)
Another person or animal (e.g. blood donor)
Herd immunity
Protect unvaccinated individuals, through having sufficiently large proportion of population vaccinated.
spread of infection can be slowed or … The unimmunised can be …. protected.
Prevented
Indirectly
Diptheria features
URTI (sore throat, low grade fever)
Wgite adherent membrane on tonsils, pharynx, and/or nasal cavity
Caused by Corynebacterium diptheriae
5in1 vaccine covers
Diptheria Tetanus Pertussis Polio HaemInfluenzaetype b (Hib)
Meningococcal Disease (Neisseria meningitidis) causes
Meningitis (35%)
Septicaemia (30%)
Men&Sept (20%)
Spread by resp droplets
Vaccination for Meningococcal disease
serogroup C
elimination of disease
reduction to zero of incidence of disease in specific geographical area
eradication of disease
permanent reduction to zero of the worldwide incidence of infection caused by a specific agent
extinction
specific infectious agent no longer exists in nature or in the laboratory
Barriers to polio eradication
cultural beliefs and programme failures (pakistan, afghnaistan, Nigeria)
re-emergence associated with conflict (ukraine, syria)
Sustaining global priority/attention
Majority of Malaria related deaths
90% in sub-saharan africa
Most cost effective health investment?
Immunisations (averts over 2 million deaths/ year)