Immune System Clinical

Question 1

** Autoimmune destruction of the pancreas beta cells mediated by CTLs is known as _________

Answer 1

insulin dependent diabetes mellitus

Question 2

** Self reactive antibodies against the AcH receptor prevents AcH from binding producing muscle weakness and autonomic dysfunction best describes _________

Answer 2

myasthenia gravis

Question 3

** Immune system attack on myeline in the CNS thought to be due to self-reactive T cells best describes _________

Answer 3

multiple sclerosis

Question 4

** T cell attack on cartilage protein in joints best describes _________

Answer 4

rheumatoid arthritis

Question 5

** In RHEUMATOID ARTHRITIS, _________ and _________ antibodies can activate MACROPHAGES leading to chronic INFLAMMATION

Answer 5

IgM

IgG

Question 6

** A long term autoimmune disease that may affect the skin, joints, kidneys, brain and other organs leading to chronic inflammation best describes _________

Answer 6

lupus erythematosis

Question 7

** In LUPAS, the breakdown in B and T cell tolerance is due to a diverse collection of _________ antibodies

Answer 7

IgG

Question 8

** There may be a link between MYASTHENIA GRAVES and _________

Answer 8

polio

Question 9

** MULTIPLE SCLEROSIS may be related to _________ and _________

Answer 9

herpes

epstein barr virus

Question 10

** An immune system attack on MYELIN in the PNS best describes _________

Answer 10

Guillain-barre

Question 11

** An inflammatory process of the SPINAL CORD that can cause axon demyelination describes _________

Answer 11

transverse myelitis

Question 12

** Genetic defect where T cells refuse to die when chronically stimulated by self antigens describes _________

Answer 12

autoimmune lymphoproliferative syndrome

Question 13

** Autoimmune lymphoproliferative syndrome is a defect in _________ due to a genetic defect in Fas or Fas Ligand proteins

Answer 13

apoptosis