Immune System and Diseases: Surface Barriers Flashcards
The first line of defence
Surface barriers
Types of surface barries
Skin and mucous membranes
How is skin a surface barrier?
-Protects external structures (outer body parts)
-Secretes lactic acid and fatty acids to lower the pH
-Has biochemical defense agents
The biochemical defense agents on the skin
Sebaceous glands secrete chemicals and enzymes which inhibit microbial growth on the skin
How is mucous membranes a surface barrier
-Protects internal structures (externally accessible cavities and tube such as esophagus, urethrae, and trachea)
-Consists of thin region of living surface cells
-Biochemical defense agents
-May be ciliated to aid in the removal of pathogens
Function of cells in mucous membranes
Release fluids to wash away pathogens
Fluids used to wash away pathogens
Mucus, saliva, tears
Secreted biochemical defense agents in mucous membranes
Lysozyme destroys cell walls and cause cell lysis
Overview of Physical and Chemical Surface Barriers
-Lysozyme in tears and other secretions
-Removal of particles by cilia in nasopharynx (nostril)
-Mucus lining trachea
-Rapid pH change in gut
-Vaginal acids (in females)
-Flushing of urinary tract)