immune system Flashcards
primary defences
- skin: dermis and epidermis
- mucous membrane
what is the mucus membrane
protects the non-skin covered area
- cells produce and secrete a lining of sticky mucous witch traps pathogens and prevents infection
- often found with cilia
what are clotting proteins
- prothrombin
- fibrogen
they block cuts at the site of injury to prevent entry of pathogens and continous bleeding
what happens when you get a cut
- damaged blood cells release chemicals that stimulate platelets to group at that area
- platelets and damaged tissue release clotting factor
- clotting factor chemicals convert prothrombin into thrombin (an active enzyme)
- thrombin catalyzes conversion of soluble fibrogin into insoluble fibrin/fibrin
secondary defences
when a pathogen enters the body;
- primary immune response; first encounter with particular pathogen
- secondary immune respose; quicker and more intense; immunity (not the first encounter)
phagocyte
white blood cells are called leucocytes
- macrophage; can change cellular shape to surround invading cell by phagocytosis
- NO REAL IMMUNITY AS ITS RANDOM
- macrophage encounters cells and determines whether it is a natural ‘self cell’ or a ‘not self cell’
- macrophage engulfs ‘not self cell’ and lyosomes chemically digest them
- macrophage encounters cells and determines whether it is a natural ‘self cell’ or a ‘not self cell’
lymphocyte
a plasma white blood cell that produces antibodies by recognizing specific bacteria by their antigen
-each lymphocyte is specific to a pathogen
antibodies; y-shaped protein moleucles produced in response to a specific pathogen; has a binding site to attach to the bacteria antigen
primary immune response
- a specific antigen type is identified
- a specific plasma cell is identified that can produce an antibody to bind to the antigen
- the specific plasma cell clones itself to increase amount
- army of plasma cells being antibody production
- antibodies find their antigen match and eliminate the pathogen
- some plasma cells remain in bloodstream and provide immunity incase of a second infection
- these ‘memory cells’ respond quickly if the same antigen is encountered again by self-replicating (SECONDARY IMMUNE RESPONSE)
HIV
human immunodeficiency virus
- infects lymphocytes and therefore causes drop in them and their antibody production
- it becomes aids (acquired immune deficiency syndrome) when person loses immune response capability
transmitted by;
- unprotected sex
- unclean needles
- pregnancy, labour, delivery and breastfeeding
- blood transfusion
antibiotics
combat bacterial infections by blocking bacteria’s metabolisms or processes (e.g.g cell wall production)
- no effect on virsues; only target prokaryotic effect with not effect on eukaryotic cells
bacterial ressistance
- bacteria divide quickly therefore can quickly mutate
- genetic variation
- resistant bacteria can rapidly repopulate colonies
- longterm and overuse of antibiotics
- in response, variations of antibiotics exist