Immune System Flashcards
Lymph Nodes function
filter lymph and help attack bacteria and viruses
Where are immune cells produced
bone marrow
Thymus
secretes thymosin - a hormone that stimulates pre T-cells to mature
Spleen
Storage Area for blood; filters blood and lymph
Adaptive Immunity lymphocytes
B-cells
T-cells
Nonspecific immune response
innate
can carry out response without learning
Types of Granulocytes
neutrophils
eosinophils
basophils
Types of Agranulocytes
lymphocytes
moncytes
lymphocyte
type of Agranulocyte
responsible for antibody production
immune system modulation
targeted killing of infected cells
monocytes
type of Agranulocyte
phagocytes that travel the body picking up foreign and domestic debris
humoral immunity
specific immune response driven by B-cells and anti-bodies
antibodies from B-cells bind to antigens on invader
they destroy invader directly or target it for attack
cell-mediated immunity
specific immune response driven by T-cells
T-cells recognize antigens displayed on cells
Some T-cells help to activate B-cells and other T-cells
autoimmunity
immune system fails to learn the distinction between self and foreign
attack self-antigens as if foreign
How are macrophages called to a site of inflammation
Through histamine and other chemicals
Histamine also vasodialates allowing macrophages to enter the tissue
Interferon
protein that prevents viral replication and dispersion
infected immune cells may produce it
Innate immune cells
macrophage mast cell granulocyte dedritic cell natural killer cell
Adaptive immune cells
B-cell
T-cell
macrophage
innate immune cell that engulfs and consumes pathogen invaders
mast cell
innate
releases histamine and other chemicals that promote inflammation
granulocyte
innate
neutrophils, eosinophil, basophil
tiny granules (bombs) in their interior
dendritic cell
innate
presents antigens - fragments of protein or other molecules from pathogens or cancer cells- to adaptive immune cells, inducing the cells to attack bearers of the displayed antigens
natural killer cell
innate
destroys body’s own cells that have become infected with pathogens; it also goes after cancer cells
b-cell
adaptive
antigens simulate cell to divide and produce antibodies that neutralize invaders or tag them for killing
t-cell
adaptive
killer t-cell
detects the presence of antigens in infected cell
other T-cells - such as helper and regulatory types - coordinate the immune response