Immune System Flashcards

1
Q

Lymph Nodes function

A

filter lymph and help attack bacteria and viruses

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2
Q

Where are immune cells produced

A

bone marrow

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3
Q

Thymus

A

secretes thymosin - a hormone that stimulates pre T-cells to mature

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4
Q

Spleen

A

Storage Area for blood; filters blood and lymph

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5
Q

Adaptive Immunity lymphocytes

A

B-cells

T-cells

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6
Q

Nonspecific immune response

A

innate

can carry out response without learning

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7
Q

Types of Granulocytes

A

neutrophils
eosinophils
basophils

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8
Q

Types of Agranulocytes

A

lymphocytes

moncytes

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9
Q

lymphocyte

A

type of Agranulocyte
responsible for antibody production
immune system modulation
targeted killing of infected cells

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10
Q

monocytes

A

type of Agranulocyte

phagocytes that travel the body picking up foreign and domestic debris

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11
Q

humoral immunity

A

specific immune response driven by B-cells and anti-bodies
antibodies from B-cells bind to antigens on invader
they destroy invader directly or target it for attack

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12
Q

cell-mediated immunity

A

specific immune response driven by T-cells
T-cells recognize antigens displayed on cells
Some T-cells help to activate B-cells and other T-cells

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13
Q

autoimmunity

A

immune system fails to learn the distinction between self and foreign
attack self-antigens as if foreign

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14
Q

How are macrophages called to a site of inflammation

A

Through histamine and other chemicals

Histamine also vasodialates allowing macrophages to enter the tissue

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15
Q

Interferon

A

protein that prevents viral replication and dispersion

infected immune cells may produce it

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16
Q

Innate immune cells

A
macrophage
mast cell
granulocyte
dedritic cell
natural killer cell
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17
Q

Adaptive immune cells

A

B-cell

T-cell

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18
Q

macrophage

A

innate immune cell that engulfs and consumes pathogen invaders

19
Q

mast cell

A

innate

releases histamine and other chemicals that promote inflammation

20
Q

granulocyte

A

innate
neutrophils, eosinophil, basophil
tiny granules (bombs) in their interior

21
Q

dendritic cell

A

innate
presents antigens - fragments of protein or other molecules from pathogens or cancer cells- to adaptive immune cells, inducing the cells to attack bearers of the displayed antigens

22
Q

natural killer cell

A

innate

destroys body’s own cells that have become infected with pathogens; it also goes after cancer cells

23
Q

b-cell

A

adaptive

antigens simulate cell to divide and produce antibodies that neutralize invaders or tag them for killing

24
Q

t-cell

A

adaptive
killer t-cell
detects the presence of antigens in infected cell
other T-cells - such as helper and regulatory types - coordinate the immune response

25
immunoglobulins
anti-bodies
26
antibody shape
y-shaped 2 identical heavy chains 2 identical light chains
27
antigen-binding region
region on tips of antibody's Y-shape that binds to antigen | specific polypeptide sequences that bind to only 1 antigen
28
constant region
involved in recruitment and binding of other immune modulators
29
B-cell daughter types
Plasma cells | Memory cells
30
plasma cells
B-cells that produces lots of anti-bodies | eventually die
31
memory cells
B-cells stay in lymph nodes will use upon re-exposure to same antigen may last lifetime of organism
32
primary response
initial activation to exposure | takes 7 - 10 days
33
secondary response
rapid and robust
34
T-cell types
helper suppressor killer
35
Helper t-cells
also called T4 cells coordinate immune response secrete lymphokines
36
killer (cytotoxic) t-cells
kill virally infected cells by secreting toxic chemicals
37
suppressor t-cells
tone down immune response once infection has been adequately contained
38
immunosuppressants
drugs that can prevent activation of the immune system
39
active immunity
immune system stimulated to produce antibodies
40
passive immunity
given the anti-bodies directly
41
lymphatic system
type of circulatory system one way vessels that become larger as they move toward center of body (heart) venous system vessels carry lymphatic fluid and join to comprise a large thoracic duct in the chest
42
lacteals
lymphatic vessels collect fats in the form of chylomicrons from the villi in the small intestine deliver them into bloodstream, bypassing liver
43
lymph nodes
nodes with immune cells (primarily B-cells)