Immune Response, HIV, Sepsis Flashcards

1
Q

what Is an antigen

A

A substance that elicits an immune response

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2
Q

what are antibodies

A

produced in response to an antigen, body produces these when antigen are present

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3
Q

what’s innate immunity

A

non specific response, present at birth, can respond within minutes, first line of defense

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4
Q

what’s acquired/adaptive immunity

A

developed immunity, gained after birth, second line of defense, gained through exposures of pathogens, can either be developed of immunity actively or passively

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5
Q

what’s active acquired/adaptive immunity

A

contact with a foreign substance or infection (immunizations are an example)

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6
Q

what’s passive acquired/adaptive immunity

A

we receive from mother, injected antibodies, this type have immediate effects but is short lived, we don’t synthesize these again therefore we don’t retain the memory for that antigen

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7
Q

humoral immunity

A

an individual exposed to an antigen for the second time, secondary antibody response occur

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8
Q

cell-mediated

A

response initiated through specific antigen recognition by T cells, T cells kill the infected cells and coordinate the overall immune response

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9
Q

what does inflammation do

A

its a sequential reaction to cell injury, removes foreign material, establishes an environment for healing, healing capacity

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10
Q

what’s a key point for inflammation

A

inflammation is always present with infection, but infection is not always present with inflammation

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11
Q

hypersensitivity responses (type 1 response)

A

igE mediated
anaphylaxis reaction from antigens (systemic), allergic rhinitis (local)

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12
Q

hypersensitivity responses (type 2 response)

A

cytotoxic
blood transfusions reaction, Rh incompatibility

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13
Q

hypersensitivity responses (type 3 response)

A

immune complex
tissue damage: systemic, local, immediate or delayed

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14
Q

hypersensitivity responses (type 4 response)

A

delayed
cell mediated response, example contact dermatitis and transplant rejections

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15
Q

latex allergies in terms of hypersensitivity responses

A

can be type 1 or type 4
type 1 is systemic (skin redness, urticaria, asthma,anaphylaxis)
type 4 is local (contact dermatitis)

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16
Q

nursing care for immunocompromised

A

masks, gowns, gloves, limit invasive procedures, limit visitors, single patient items, no raw/uncooked veggies, no sharing razors, toothbrush

17
Q

nursing care for gerontologic

A

decline in function of immune system, increased susceptibility to infection, response to immunizations is lower, thymus shrinks, t-cells production diminishes

18
Q

sepsis criteria

A

2+ of the following
AMS, temp >100.9, HR >90, hyperglycemia w/o DB >140, Hypothermia <97, SBP <100, RR >22

19
Q

how is HIV spread

A

blood, semen, breast milk, vag secretions

20
Q

what does HIV cause

A

immunosuppression

21
Q

what’s AIDS

A

a point on the continuum of HIV infection where they are severely immunocompromised, AMS, Labs worse

22
Q

what are opportunistic infections

A

infections that take over people who are like immunocompromised like AIDS