Immune Response Flashcards

1
Q

1st line of defense

A

Innate response

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2
Q

types of cells in the adaptive response

A

T cells and B cells

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3
Q

types of T cells

A
  • Helper T cells
  • Cytotoxic T cells
  • Memory T cells
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4
Q

Types of B cells

A
  • Naive B cells
  • Activated B cells
  • Plasma B cells
  • Memory B cells
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5
Q

Types of cells in native response

A
  • Basophils
  • Neutrophils
  • Macrophage
  • MAST Cells
  • Natural Killer (NK) cells
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6
Q

Chemical mediators in Innate response

A

Cytokines- Interleukins/ histamines/ heparin

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7
Q

Chemical mediators in adaptive response

A

Cytokine/ antibodies

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8
Q

action time of native response

A

0-24 Hours (quick)

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9
Q

action time of adaptive response

A

days- weeks (slower)

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10
Q

Which immune response has specificity?

A

Adaptive response

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11
Q

Which response has memory?

A

Adaptive response

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12
Q

Which response has the highest potency?

A

Adaptive response

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13
Q

4 signs of infection

A
  1. Increased temp
  2. redness
  3. swelling
  4. pain
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14
Q

Stages of catching neutrophils on the endothelial cells

A

1) recruitment
2) captured
3) rolling
4) arrest
5) diapedesis/ extravasation

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15
Q

MAST Cell function

A

Release histamine and heparin which causes increased blood flow and permeability

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16
Q

neutrophils

A

first responder of the immune system, produce antimicrobial substances and enzymes to kill microbes

17
Q

Reactive oxygen species function

A

signaling molecules that induce endocytosis, netosis, and secretes interleukins (IL-1b and IL-1a)

18
Q

Macrophage function

A

engulfs and digests pathogens

19
Q

Major Histocompatibility Complex II function

A

Protein that initiates immune responses

20
Q

IgG binds to

A

antigens

21
Q

IgD binds to

A

basophils and MAST cells

22
Q

IgE binds to

A

B-cells

23
Q

IgA binds

A

in mucous

24
Q

IgM is secreted

A

First

25
Q

Plasma cells make

A

antibodies