immune principles and serological techniques Flashcards
serological techniques detect what in body fluids
antibodies or antigens
A hapten is…
A small molecule that stimulates the immune system when bound to a carrier
Immunogen is….
A substance that initiates a detectable immune response
Antigen-Antibody Reaction is…
An immunogen combining with an antibody
Epitope is…
Antigenic determinant
Antibody is…
An immunoglobulin capable of combining, with specificity, to the antigen that elicited its production
Allergen is…
An immunogen that elicits an allergic response
Antigen is…
A substance that interacts with cells or molecules of the immune response
classifications of antibodies
IgG
IgA
IgM
IgD
IgE
IgG function
Major antibody in secondary immune response
IgM function
Major antibody in primary immune response
IgA function
Antibody found primarily in secretory forms
IgE function
Antibody primarily related to allergies
True or False : The definition of a titer is -
The greatest dilution at which an antibody and its corresponding hapten still react
False
Clinically significant titer is…
A 4x (two-tube) increase between acute and convalescent titers
Acute titer is…
Concentration of antibody present during the acute phase of the disease
Convalescent titer is…
Concentration of antibody present two weeks after onset of infection
Prozone is…
Antibody excess
Zone of equivalence is…
concentration of antibody and antigen is optimal allowing for a lattice to form
Postzone is…
antigen excess
Direct agglutination is…
Antigen is a natural partical
Adsorption is…
Process of adhering a particle to a solid surface
Indirect agglutination is…
Antigen is Adsorbed onto the surface of a particle
Absorption is…
Process of pulling particles into a substance
Hemagglutination is…
RBCs are used as the solid phase / particle
