immune principles and serological techniques Flashcards

1
Q

serological techniques detect what in body fluids

A

antibodies or antigens

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2
Q

A hapten is…

A

A small molecule that stimulates the immune system when bound to a carrier

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3
Q

Immunogen is….

A

A substance that initiates a detectable immune response

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4
Q

Antigen-Antibody Reaction is…

A

An immunogen combining with an antibody

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5
Q

Epitope is…

A

Antigenic determinant

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6
Q

Antibody is…

A

An immunoglobulin capable of combining, with specificity, to the antigen that elicited its production

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7
Q

Allergen is…

A

An immunogen that elicits an allergic response

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8
Q

Antigen is…

A

A substance that interacts with cells or molecules of the immune response

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9
Q

classifications of antibodies

A

IgG
IgA
IgM
IgD
IgE

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10
Q

IgG function

A

Major antibody in secondary immune response

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11
Q

IgM function

A

Major antibody in primary immune response

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12
Q

IgA function

A

Antibody found primarily in secretory forms

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13
Q

IgE function

A

Antibody primarily related to allergies

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14
Q

True or False : The definition of a titer is -
The greatest dilution at which an antibody and its corresponding hapten still react

A

False

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15
Q

Clinically significant titer is…

A

A 4x (two-tube) increase between acute and convalescent titers

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16
Q

Acute titer is…

A

Concentration of antibody present during the acute phase of the disease

17
Q

Convalescent titer is…

A

Concentration of antibody present two weeks after onset of infection

18
Q

Prozone is…

A

Antibody excess

19
Q

Zone of equivalence is…

A

concentration of antibody and antigen is optimal allowing for a lattice to form

20
Q

Postzone is…

A

antigen excess

21
Q

Direct agglutination is…

A

Antigen is a natural partical

22
Q

Adsorption is…

A

Process of adhering a particle to a solid surface

23
Q

Indirect agglutination is…

A

Antigen is Adsorbed onto the surface of a particle

24
Q

Absorption is…

A

Process of pulling particles into a substance

25
Q

Hemagglutination is…

A

RBCs are used as the solid phase / particle