immune popcorn Flashcards

1
Q

allergic and helminth responses

A

basophils

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2
Q

release histamine and heparin

A

basophils and mast cells

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3
Q

reduction of clotting

A

heparin basophils

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4
Q

least common PNM

A

basophils

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5
Q

circulating in bloodstream and present in organs particularly GI and Respiratory tract

A

eosinophils

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6
Q

release H2o2 and oxygen radicals

A

eosinophils

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7
Q

viruses and parasites

A

eosinophils

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8
Q

release leukotrienes (lipid signaling)

A

eosinophils

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9
Q

active in allergic reactions and asthma

A

eosinophils

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10
Q

stimulate Tlymphocytes and are weakly phagocytic

A

eosinophils

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11
Q

most abundant granulocyte

A

Neutrophils

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12
Q

circulating the blood stream

A

Neutrophils

basophils

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13
Q

active against fungi and bacteria

A

Neutrophils

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14
Q

first responders

A

Neutrophils

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15
Q

release other cytokines to recruit monocytes & macrophages

A

Neutrophils

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16
Q

Strongly Phagocytic

A

Neutrophils

17
Q

Neutrophil Extracellular Traps (NETs)

A

Neutrophil

18
Q

fever

A

IL 1 and 6

19
Q

acute phase response

A

IL-6

20
Q

activates activates neutropjils

A

TNF

21
Q

block virus replication

A

interferons

22
Q

mature in tissues

A

mast cells

23
Q

agranular

A

monocytes

rise to dendritic cells & macrophages

24
Q

stored in spleen

A

monocytes

25
Q

strongest APC

A

dendritic cells

26
Q

langerhans cells

A

dendritic cells

hiv

27
Q

release TNF and ILs

A

macrophages

28
Q

Specialized macrophages within the liver

Destroy bacteria & old RBCs

A

kupffer cells

29
Q

Chronic activation of Kupffer cells (toxins, EtOH

A

liver damage

30
Q

against viruses and cancerous cells

A

NKC

31
Q

perforins and proteases

A

NKC

32
Q

bloodstream, liver and spleen

A

NKC

33
Q

made in liver

A

complement proteins

34
Q

c3

A

most abundant complement protein in humans

35
Q

Opsonization

A

enhancing phagocytosis of antigens by ‘marking’ them for destruction