Immune

Question 1

When in the course of a transplant will a patient be susceptible to opportunistic infections?

Answer 1

After 1 month of starting immunosuppressive medications`

Question 2

When is GVH most common?

Answer 2

!st 100 days of transplant

Question 3

How often do stem cell transplant patients have GVHD?

Answer 3

50%

Question 4

What are the symptoms in the first week of GHVD?

Answer 4

Rash, fever, leading to hepatitis, fluid retention, shock

Question 5

What is the treatment for chronic GVHD?

Answer 5

Steroids

Question 6

What must be done to the pRBCs prior to transfusion for a patient with any type of transplant?

Answer 6

Irradiated

Question 7

What are the s/sx of a kidney transplant rejection?

Answer 7

HTN, decreased uop, increased creatinine

Question 8

What are the primary s/sx of a lung transplant rejection?

Answer 8

SOB

CXR with infiltrates

Question 9

Why does atropine not work for cardiac transplant patients?

Answer 9

Vagus nerve is not replaced during transplant

Question 10

What are the reversal agents for angioedema?

Answer 10

Icatibant

Ecallantide

Question 11

What is DRESS syndrome? s/sx?

Answer 11

Drug related eosinophilia with systemic symptoms

Fever, rash, eosinophilia, transaminitis, atypical lymphocytes

Question 12

What is the mortality rate with DRESS?

Answer 12

10%–they’re sick

Question 13

What is the treatment for raynaud’s?

Answer 13

CCB

Question 14

What are the components of CREST syndrome?

Answer 14

Calcinosis
Raynaud's
Esophageal dysmotility
Sclerodactyly
Telangiectasias

Question 15

What are the manifestations of scleroderma crisis (heart, lungs, kidneys)

Answer 15

• Renal crisis/HTN
• pHTN, alveolar hemorrhage
• CHF, arrhythmias

Question 16

What is the emergent complication from dermatomyositis?

Answer 16

Rhabdo

Question 17

What is the treatment for dermatomyositis (from the ER)?

Answer 17

Steroids

Question 18

Gower’s sign = ?

Answer 18

Polymyositis

Question 19

What are the s/sx of polymyositis?

Answer 19

Proximal muscle weakness, Gower’s sign

Question 20

What is the treatment for polymyositis?

Answer 20

Steroids, immunosuppressants

Question 21

What is Behcet’s syndrome, and what are the s/sx?

Answer 21

Systemic vasculitis that classically causes painful oral/genital ulcers, uveitis, erythema nodosum

Question 22

What is the inheritance pattern of Marfan’s syndrome?

Answer 22

AD

Question 23

What infection is associated with polyarteritis nodosa?

Answer 23

Hep B

Question 24

What organ system is typically spared with polyarteritis nodosa?

Answer 24

Lungs

Question 25

beads on a string appearance of the renal arteries = ?

Answer 25

Polyarteritis nodosa

Question 26

What vessel is classically affected with Takayasu arteritis?

Answer 26

Aorta and its branches

Question 27

ESR over what level is characteristic of giant cell arteritis?

Answer 27

50

Question 28

What is the eponym for thromboangiitis obliterans?

Answer 28

Burger’s disease

Question 29

What skin finding is commonly associated with sarcoidosis?

Answer 29

Erythema nodosum

Question 30

What enzyme level is elevated with sarcoidosis?

Answer 30

ACE

Question 31

What EKG finding may be present on a patient with rheumatic fever?

Answer 31

Prolonged PR

Question 32

Which step associated problem is preventable with PCN treatment: rheumatic fever or glomerulonephritis

Answer 32

Rheumatic fever is preventable, glomerulonephritis is not