Imm 0 Flashcards

1
Q

What muscles and nerves are derived from the first brachial arch?

A

[The Ms and Ts] Muscles (muscles of mastication, mylohyoid muscle, Tensor tympani, Tensor veli palatini). Nerves (Maxillary and mandibular division of the trigeminal nerve).

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2
Q

Which amino acids are found in large concentrations in elastin?

A

Glycine and proline.

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3
Q

What is the mechanism of action of adenosine as an antiarrhythmic?

A

Increases the outward K+ current, hypolarizing the cell, and decreases intracellular Ca2+.

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4
Q

What muscles and nerves are derived from the second brachial arch?

A

[The S’s] Nerve: CN Seven (muscles of facial expression). Muscle: Stapedius, Stylohyoid.

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5
Q

What is the antidote for opioids?

A

Naloxone or naltrexone.

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6
Q

What is the antidote for Benzodiazepines?

A

Flumazenil.

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7
Q

What is the antidote for Tricyclic antidepressants?

A

Alkalinize the urine w/ sodium bicarb.

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8
Q

What is the antidote for Heparin?

A

Protamine.

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9
Q

What is the antidote for Warfarin?

A

Vitamin K. Immediate antidote is fresh frozen plasma.

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10
Q

What is the antidote for Theophylline?

A

Beta blockers.

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11
Q

How does hyperkalemia affect the shape of T waves?

A

Tall, peaked T waves. (T waves mirror the K+ levels).

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12
Q

What muscles and nerves are derived from the third brachial arch?

A

Muscle: Stylopharyngeus muscle. Nerve: Glossopharyngeal nerve (CN IX).

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13
Q

What drug category is often used in the treatment of myasthenia gravis?

A

Acetylcholinesterase inhibitors (Ex: pyridostigmine, physostigmine).

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14
Q

To which class of antiarrhythmics does Sotalol belong?

A

Technically a Beta blocker but strongest action is on K+ channels which would make it Class III.

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15
Q

To which class of antiarrhythmics does Propranolol belong?

A

Beta blockers are Class II.

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16
Q

To which class of antiarrhythmics does Bretylium belong?

A

Class III.

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17
Q

To which class of antiarrhythmics does Quinidine belong?

A

Class I.

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18
Q

What muscle and nerves are derived from the fourth and sixth brachial arch?

A

Muscles: Cricothyroid, Levator veli palatini, and all of the muscles of the larynx. Nerves: Recurrent laryngeal, superior laryngeal.

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19
Q

What defect is associated with the following type of murmur: Pansystolic (holosystic) murmur best heard at the apex, often radiates to the left axila.

A

Mitral regurgitation.

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20
Q

What defect is associated with the following type of murmur: Crescendo/decrescendo systolic murmur heard best in the 2nd-3rd right interspace close to the sternum.

A

Aortic stenosis.

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21
Q

What defect is associated with the following type of murmur: Late systolic murmur usually preceded by a mid-systolic click.

A

Mitral prolapse.

22
Q

What defect is associated with the following type of murmur: Early diastolic decrescendo murmur heard best along the left side of the sternum.

A

Pulmonic regurgitation.

23
Q

What defect is associated with the following type of murmur: late diastolic decresendo murmur heard best along the left side of the sternum.

A

Tricuspid stenosis.

24
Q

What heart defect is associated w/ Chromosome 22q11 deletion?

A

Truncus arteriosus and tetralogy of Fallor.

25
What heart defect is associated w/ Congenital rubella?
PDA or pulmonary artery stenosis.
26
What heart defect is associated w/ Turner syndrome?
Coarctation of the aorta and bicuspid aortic valve.
27
What heart defect is associated w/ Marfan syndrome?
Aortic insufficiency.
28
Which organism's exotoxin works via the following mechanism: Inactivates EF-2.
Corynbacterium diphtheriae. Pseudomonas (exotoxin A).
29
Which organism's exotoxin works via the following mechanism: Activates Gs.
Vibrio cholerae. E.coli (ETEC heat-labile toxin).
30
Which organism's exotoxin works via the following mechanism: Disables Gi?
Pertussis toxin.
31
Which organism's exotoxin works via the following mechanism: Bacterial adenylate cyclase (no G protein involved).
Bacillus anthracis.
32
Which organism's exotoxin works via the following mechanism: Blocks GABA and glycine.
Clostridium tetani.
33
What drug is used to help make the diagnosis of myasthenia gravis?
Edrophonium ("Tensilon test").
34
What heart sound is associated w/ dilated congestive heart failure? With chronic hypertension and a stiffened left ventricle?
For Dilated CHF: S3 heart sound. Chronic HTN + Stiffed LV: S4 heart sound.
35
What gives rise to the jugular venous a, c, and v waves?
A wave: atrial contraction. C wave: ventricular contraction. V wave: Atrial filling against closed tricuspid valve.
36
Which heart murmur is associated w/ weak pulses?
Aortic stenosis.
37
What findings are associated w/ Ehlers-Danlos syndrome?
Easy bleeding or bruising. Hyperextensible skin. Joint hypermobility. Dislocated joints. Aneurysms.
38
What heart sounds are considered benign when there is no evidence of disease?
Split S1. Split S2 on inspiration. S3 heart sound in patient less than 40. Early, quiet systolic murmur.
39
Which organisms do not take Gram stain?
Treponema (too thin). Rickettsia, Chlamydia, Legionella (they are intracellular). Mycoplasma (no cell wall). Mycobacteria (too much lipid in their cell wall).
40
What is the Cause of Duchenne's muscular dystrophy?
Deletion of gene for dystrophin. Degeneration of individual muscle fibers.
41
A pregnant patient comes to the clinic complaining of new dark pigmentation on her face. What is the likely diagnosis?
Melasma (mask of pregnancy).
42
A woman that is breastfeeding develops redness and swelling of her right breast over a period of 24 hours. Examination reveals a warm, fluctuant mass. What is the diagnosis?
Mastitis.
43
A 55-y.o man who is a smoker and heavy drinker presents w/ a new cough and flu-like symptoms. Gram Stain shows now organisms; silver stain of sputum shows gram-negative rods. What is the diagnosis?
Legionella pneumophila (Legionnaire's disease).
44
What defect is associated with the following type of murmur: Rumbling late diastolic murmur w/ an opening snap.
Mitral stenosis.
45
What defect is associated with the following type of murmur: pansystolic (or holosystolic) murmur best heard along the left lower sternal border, generally radiates to the right lower sternal border.
Tricuspid regurgitation. Ventricular septal defect.
46
What defect is associated with the following type of murmur: high-pitched diastolic murmur associated w/ a widened pulse pressure.
Aortic regurgitation.
47
What defect is associated with the following type of murmur: Cresscendo/decrescendo systolic murmur heard best at the 2nd-3rd left interspace close to the sternum.
Pulmonic stenosis.
48
What defect is associated with the following type of murmur: continuous machine-like murmur occuring both in systole and diastole?
Patent ductus arteriosus.
49
Which antiarrhythmic has the SE of cinchonism?
Quinidine.
50
What stain is required to see Cryptococcus?
India ink.
51
What stain is required to see PCP?
Silver stain.
52
What stain is required to see Chlamydia?
Giemsa stain.