imaging Flashcards

1
Q

5 medical imaging modalities for cancer screening

A
  1. X-rays
  2. ultrasound
  3. Computed tomography (CT)
  4. magnetic resonance imaging (MRI)
  5. Positron emission tomography (PET)
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2
Q

which modalities are the only ones which are ionising?

A

CT and PET

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3
Q

Pros of Ultrasound

A
  1. Bedside
  2. good evaluation of solid abdominal organs and superficial structures (e.g. breast, thyroid etc…)
  3. good spatial resolution
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4
Q

cons of ultrasound

A
  1. user dependent
  2. limited penetration
  3. blind spots
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5
Q

pros of CT

A
  1. good for unstable patients
  2. good for hollow organs, bones, blood
  3. reasonable soft tissue contrast
    4 .excellent spatial resolution
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6
Q

cons of CT

A
  1. hard to evaluate tissue properties
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7
Q

pros of MRI

A
  1. excellent soft tissue contrast
  2. excellent evaluation of tissue properties
  3. v good spatial resolution
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8
Q

cons of MRI

A
  1. it takes a while
  2. enclosed space
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9
Q

pros of PET

A
  1. high sensitivity for detection of metabolically active tumours
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10
Q

cons on PET

A
  1. poor spatial resolution
  2. false positives
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11
Q

MRI: what can enhancement/ elevated perfusion indicate

A
  1. increased capillary density
  2. capillary permeability

useful for establishing tumour grade

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12
Q

MRI: diffusion-weighted imaging

A
  1. reflects cellularity of tumour
  2. low diffusion indicates densely cellular tumour
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13
Q

MRI: what brain tumours can be detected by diffusion-weighted imaging

A
  1. lymphoma
  2. medulloblastoma
  3. atypical teratoid rhabdoid tumours
  4. germinomas
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14
Q

what can magnetic resonance spectroscopy indicate about a tumour

A
  1. increase choline
  2. decrease NAA
  3. increase in inositol
  4. increase in mobile lipids
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15
Q

what does progressive disease (PD) mean

A

≥ 20% increase in the sum of diameters of target lesions

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16
Q

what does stable disease (SD) mean

A

neither sufficient shrinkage for partial response nor increase for progressive disease

17
Q

what does partial response (PR) mean

A

at least a 30% decrease in the sum of length diameters (SLD) of target lesions

18
Q

what does complete response (CR) mean

A

disappearance of all target and non-target lesions

19
Q

what does the T in TNM staging mean

A

the side of the original tumour and local invasion

20
Q

what does the N in TNM staging mean

A

regional lymph node involvement

21
Q

what does the M in TNM staging mean

A

distant metastasis

22
Q

what is pseudoprogression

A

aggressive appearing treatment effects

23
Q

when is pseudoregression mainly seen

A

with anti-angiogenic agents