Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PLE Review > IM-Rheuma and Immu > Flashcards

IM-Rheuma and Immu Flashcards

1
Q

Clear, viscous, amber-colored, WBC <2000/ul

Predominance of mononuclear cells

A

Non-inflammatory fluid

E.g Gout

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Clear or pale straw, viscous

A

Normal synovial fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Opaque, purule t, WBC >50000/ul

PMN predominance

Reduced viscosity

A

Septic fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Turbud, yellow, WBC 2000-50000/ul

PMN predominance, reduced viscosity

Little or no tail following each drop

A

Inflammatory fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Differentiate OA from RA in

Morning stiffness duration
Joints involves
Joint fluid leukocyte count
Treatment

A 
OA
<30min
DIP, PIP
<2000 leukocyte
Acetaminophen: initial analgesic of choice
NSAID: most popular
RA
>1hr
MCP, PIP
>5000-50000 leukocyte
\+RF, +anti CCP
DMARDs (Methotrexate)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Severe OA of hands affecting DIP

Severe OA of hands affecting PIP

A

Heberden’s nodes

Bouchard’s nodes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Pathologic hallmarks of RA

Frequent hallmark of RA

Define
Boutonniere deformity
Swan-neck deformity
Z-line deformity

A

Synovial inflammation
Flocal bone erosions
Thinning of articular cartilage

Flexor tenosynovitis

Flexion of PIP, hyperextension of DIP
Hyperextension of PIP, flexion of DIP
Subluxation of 1st MCP, hyperextension of 1st IP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Felty’s syndrome TRIAD

A

Nodular RA
Splenomegaly
Neutropenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Most common hematologic abnormality of RA

Most common pulmonary manifestation of RA

Most common valvular abnormality of RA

Initial radiographic finding of RA

A

normocytic normochromic anemia

Pleuritis

Mitral regurgitation

Periarticular osteopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Most common early clinical manifestation of gout

Classic initial presentation of gout

Diagnostic test for gout

Drugs that causes hyperuricemia

A

Acute arthritis (1st MTP)

Podagra

Arthrocentesis

Thiazide
Niacin
Alcohol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Differentiate gout from pseudogout microscopically

A

Gout
Negatively birefringent
Needle-shaped
monosodium urate crystals

Pseudogout
Positively birefringent
Rhomboid-shaped
Calcium pyrophosphate dehydrate crystals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Mainstay of tx suring acute gouty attack

Hypouricemic therapy for:

  1. Underexcreter
  2. Overproducer
A

NSAID 1st line (indometha kn, naproxe , ibuprofen, diclofenac, celecoxib)
Colchicine
Glucocorticoids

  1. Probenecid, benzbromarone, sulfunpyrazone
  2. Allopurinol, febuxostat
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

SLE drugs for non life threatening dse:

Mainstay
Arthritis/arthralgia
Dermatitis

SLE drugs for life threatening dse:

Mainstay
Lupus nephritis
Severe thrombocytopenia
Disease relapse

A

Analgesics and antimalaris
NSAIDS
Antimalarials (hydroxychloroquine, chloroquine, quinacrine)

Systemic glucocorticoids PO/IV
High dose glucocorticoid pulse
High dose glucocorticoid pulse
Cyclophosphamide (nausea), Azathioprine, Mycophenolate mofetil (diarrhea)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Drug-induced lupus causes

(+) antihistone

A 
Hydralazine
Isoniazid
Phenytoin
Procainamide
PTU
Statins
Sulfalazine
Nitrofurantoin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Most serious manifestation of SLE

Leading cause of mortality on the first decade

Most common manifestation of

  1. diffuse CNS lupus
  2. Pulmonary
  3. Cardiac
  4. Serious cardiac
  5. Valvular involvement
  6. Musculoskeletal
  7. Cutaneous
A

Nephritis

Nephritis and infection

  1. Cognitive dysfunction
  2. Pleuritis
  3. Pericarditis
  4. Myocarditis, libman sacks endocarditis
  5. Mitral or aortic
  6. Arthralgia/myalgia
  7. Photosensitivity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Evanescent migrating rash

First degree AV block

A

Rheumatic fever

17
Q

Expanding bull’s eye rash (erythema migrans)
Complete heart block
Tick bite

A

Borrelia burgdoferi

18
Q

Multiple target appearing plaque

Drug exposure

A

Erythema multiforme

19
Q

Duration of prophylaxis in RF

RF without carditis
RF with carditis, no valvular involvement
RF with carditis with valvular involvement

A

5 years from last attack or until 21yo

10 years from last attack or until 21yo

10 years from last attack or until 40yo

whichever is LONGER

20
Q

Scleroderma

Tx for
GERD
Fibrosis
Raynauds
Renal hypertensive crisis
A

PPI
Cyclophosphamide
CCB
ACE inhinitor

21
Q

Most potent drug for treatment of rhinitis

Standard of management for nasal congestion

A

Intranas glucocorticoids

Alpha adrenergic agonist:
Pseudoephedrine (+antihistamine)

PLE Review (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions