IM Arthropathies Flashcards

1
Q

Non articular/ Articular:

Deep/diffuse pain or limited ROM during passive and active movement
• Swelling, crepitation, instability, deformity
• Examples: see algorithms

A

Articular

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2
Q

Non articular/ Articular:

Painful on active (but not passive) ROM
• Seldom with swelling, crepitus, instability
• Examples: trauma/fracture, fibromyalgia,
polymyalgia rheumatica, bursitis, tendinitis

A

Non articular

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3
Q

Commonly affected joints: Cervical and lumbosacral spine, Hip,
Knee, first MTP joint, hand joints (DIP, PIP)

A

OA

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4
Q

Joint space loss or narrowing is a typical radiographic finding

A

OA

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5
Q

Manifests as DIP and PIP pain with bony hypertrophy sufficient to produce Heberden’s and Bouchard’s nodes; pain +/-swelling involving base of thumb (1st carpometacarpal joint)

A

OA

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6
Q

Cause symmetric, polyarticular involvement of PIP, MCP, intercarpal, and carpometacarpal joints (wrist) with pain

A

RA

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7
Q

Single most accurate test for RA

A

Anti CCP Ab

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8
Q
  • Flexor tenosynovitis (frequent hallmark)
  • “Swan-neck deformity”
  • “Boutonniere deformity”
  • “Z-line deformity
A

RA

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9
Q
  • Ulnar deviation from subluxation of the MCP joints
  • Ulnar deviation from subluxation of the MCP joints
  • Piano-keymovementofulnarstyloid
A

RA

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10
Q

Pathologic hallmarks of RA
oSynovial inflammation
oFocal bone erosions
oThinning of articular cartilage

A

RA

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11
Q

RA: most common pulmonary manifestation.

A

Pleuritis

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12
Q

Most common Valvulopathy in RA

A

Mitral Regurgitation

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13
Q

Nodular RA
Splenomegaly
Neutropenia.

A

Felty’s syndrome

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14
Q

Initial radiographic Finding in RA

A

Periarticular osteopenia

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15
Q

Male, sudden, knee & big toe, comorbids, presence of inflammation

A

Gout

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16
Q

Needle shaped monosodium urate crystals

negative birefringence

A

Gout

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17
Q

Rhomboid shaped Calcium pyrophosphate dehydrate crystals

A

Pseudogout

18
Q

How much 24 hr urine Uric Acid to be
Overproducer?
Underexcreter?

A

> 800

<800

19
Q

Conditions positive with RF:

S
S
s
H

A

SLe
Sjogren’s
Subactue bacterial endocarditis
Hepatitis B and C

20
Q

You have a patient with RA who suddenly has dry cough, progressive shortness of breath, you are to think of ???``

A

ILD

21
Q

Best initial DMARD for RA

A

Methotrexate

22
Q

Most common early clinical manifestation of gout

A

Acute Arthritis

23
Q

Classic inital presentation of gout

A

Podagra

24
Q

Commonly affected joints in OA

A

Cervical, lumbosacral spine, hip , knee, 1st MTP

25
Q

Most frequently involved joints in RA

A

wrist, mcp, PIP

26
Q

Hallmark of RA and leads to decreased ROM

A

Flexon tendon tenosinuvitis

27
Q

sicca, xerostomia + RA

What do you have?

A

Sjogren’s

28
Q

During acute attack of gout give uric acid lowering agents.

True or fals

A

False.

Avoid in acute attacks.
just give nsaids, the short acting ones, ibuprofen, indomethacin

29
Q

Offers greatest sensitivity for detecting synovitis & joint effusions; and early bone/bone marrow changes

A

MRI

30
Q

Characteristic radiographic features
oDIP involvement or Pencil-in-cup deformity
o Marginal erosions with adjacent bony proliferation
(“whiskering”)
oSmall joint ankylosis
o Osteolysis of phalangeal and metacarpal bone, with telescoping
of digits
oPeriostitis and proliferative new bone at sites of enthesitis oCharacteristics of axial PsA: asymmetric sacroiliitis

A

Psoriatic Arthritis

31
Q

Young adult, fever, chills, rash and articular symptoms =

A

Think of disseminated gonococcal arthritis

32
Q

In Lupus Nephritis start using Steroids in what stage

A

Lupus II

33
Q

In Lupus Nephritis start using Cyclophosphomide in what stage

A

Lupus III

34
Q

best screening For SLE

A

ANA

35
Q

specific and correlate with disease activity for SLE

A

Anti DSDNA

36
Q

LE: specific

A

Anti Sm

37
Q

Increased in SLE with overlap features of other CTD’s

Sicca syndrome, subacute cutaneous lupus, neonatal lupus with CHB

both are associated with DECREASED risk for nephritis) drug induced lupus (MC: hydralazine, procainamide, quinidine, INH, minocycline)

Antiphospholipid: clotting

useful in distinguishing lupus cerebritis and steroid-induced psychosis

A

Anti RNP

Anti RO SSA

Anti La SSB

Anti Histone

Antiphospholipid

Anti neuronal and Anti Ribosomal P

38
Q

Drugs in associated with Drug induced Lupus

A
procainamide,
 hydralazine,
 propylthiouracil,
 lithium,
 phenytoin,
 isoniazid,
nitrofurantoin,
 sulfasalazine, 
statin
39
Q

Marginal erosions with adjacent bony proliferation

A

Ps A

40
Q
  1. Joint space loss or narrowing
    _______2. Periarticular osteopenia as the initial radiographic
    finding
    _______3. Cystic changes with well-defined erosions and overhanging sclerotic margins and soft tissue masses
    _______4. DIP involvement or Pencil-in-cup deformity
A

OA

RA

Gout

PsA

41
Q
  1. A 60-year old woman with left hip pain during walking stairs and bony enlargement of the first DIP.
    _______2. A 22-year-old woman cervical discharge, rashes on forearms and elbow swelling and tenderness.
    _______3. A 40-year-old man with swollen and painful 1st MTP joint after a binge drinking.
    _______4. A 40-year-old woman with morning joint stiffness and bilateral ulnar deviation.
    _______5. A 30-year-old woman with joint pain, photosensitive erythematous rash on the face and anemia.
A

OA

Gonococchal Arthritis

Gout

RA

SLE