ILD

Question 1

Which of the following type of interstitial lung disease resolves with smoking cessation

Answer 1

Distal interstitial pneumonia (DIP) and respiratory associated bronchiolitis associated interstitial lung disease (RBILD)

Question 2

With Pirfenidone for treatment of idiopathic pulmonary fibrosis, which of the following parameter is unlikely to improve

Answer 2

Dyspnoea scores

Reduced disease progression, as reflected by lung function, exercise tolerance, and progression-free survival

Question 3

Role of Pirfenidone in IPF

Answer 3

Reduced disease progression, as reflected by lung function, exercise tolerance, and progression-free survival
S/E photosensitivity, deranged LFT

Question 4

Cystic fibrosis patients with which mutation would benefit most from treatment with CTFR modulators
tezacaftor and ivacaftor

Answer 4

Phe508 del mutation

Question 5

Cut off value for DLCO for transplant referral

Answer 5

DLCO<40%

Question 6

ILD associated with Sjogrens

Answer 6

Lymphocytic interstitial pneumonitis

Question 7

ILD associated with poor survival

Answer 7

Acute interstitial pneumonitis

Question 8

MOA of nintedanib in ILD

Answer 8

Tyrosine kinase inhibitor targeting PDGF,FGF, VEGF

S/E -diarrhoea, nausea, deranged LFT

Question 9

Independent predictor of mortality in IPF

Answer 9

Extent of honeycombing and reticulation