COPD

Question 1

Which intervention has no proven survival benefit in COPD

Answer 1

Long-acting beta-agonists and inhaled corticosteroids
Smoking cessation improves survival
Oxygen therapy, lung volume reduction surgery, or lung transplantation may also improve survival.

Question 2

Role of NO in asthma

Answer 2

Nitric Oxide is derived from the airway epithelium and promotes dilatation of blood vessels and airways
Fractional nitric oxide (NO) concentration in exhaled breath (FENO) -quantitative, noninvasive, simple and safe method of measuring airway inflammation.

Question 3

CODEX index

Answer 3

comorbidity, obstruction, dyspnea, and previous severe exacerbations index can accurately predict mortality, hospital readmission, and their combination for the period from 3 months to 1 year after discharge in patients hospitalized for COPD.

Question 4

Factor unchanged with pulmonary rehab

Answer 4

Lung function test

Pulmonary rehab improves ET, QOL

Question 5

BODE index to predict risk of death in COPD

Answer 5

Distance walked in 6min
%FEV1
Dyspnoea index
BMI

Question 6

MOA of dupilumab in asthma

Answer 6

Anti interleukin 4 receptor alpha monoclonal ab

Blocks IL-4 and IL-13