ILD

Question 1

how do you investigate ILD? what do you find?

Answer 1

HRCT - ground glass appearance

?lung biopsy - histology

Question 2

how does idiopathic pulmonary fibrosis present?

Answer 2

insidious onset SOB

dry cough > 3months

Question 3

complications of idiopathic pulmonary fibrosis ?

Answer 3

resp failure –> pulmonary HTN –> cor pulmonale

Question 4

typical presentation?

Answer 4

50 year old presents with finger clubbing and bibasal fine inspiratory crackles

Question 5

medical management of idiopathic pulmonary fibrosis ?

Answer 5

pirfenidone

nintedanib

Question 6

which drugs can cause pulmonary fibrosis?

Answer 6

1. Amiodarone
2. Cyclophosphamide
3. Methotrexate
4. Nitrofurantoin

Question 7

which conditions cause secondary pulmonary fibrosis?

Answer 7

1. Alpha-1 antitripsin deficiency
2. Rheumatoid arthritis
3. Systemic lupus erythematosus (SLE)
4. Systemic sclerosis

Question 8

which type of hypersensitivity reaction happens in hypersentivity pneumonitis?

Answer 8

type III hypersenstivity reaction to environmental allergen

Question 9

how do you diagnose hypersentivity pneumonitis?

Answer 9

bronchoalveolar lavage using bronchoscopy - shows mast cells and lymphoctyes

Question 10

examples of specific causes of hypersentivity pneumonitis?

Answer 10

Bird-fanciers lung
Farmers lung
Mushroom workers’ lung
Malt workers lung

Question 11

managment of hypersenstivity pneumonitis?

Answer 11

remove allergen
give oxygen
steroids

Question 12

what is Cryptogenic organising pneumonia?

Answer 12

inflammation in a focal area of the lung

also known as bronchiolitis obliterans organising pneumonia

Question 13

how does it look like on CXR?

Answer 13

focal consolidation

Question 14

definitve investiagtion ?

Answer 14

lung biopsy