IID 20: Antimicrobial Stewardship and Resistance Flashcards

1
Q

What antibiotics target the cell wall?

A
  • beta-lactams
  • vancomycin
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2
Q

What antibiotics target DNA/RNA synthesis?

A
  • fluoroquinolones
  • rifamycins
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3
Q

What antibiotics target folate synthesis?

A
  • trimethoprim
  • sulfonamides
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4
Q

What antibiotics target the cell membrane?

A

daptomycin

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5
Q

What antibiotics target protein synthesis?

A
  • linezolid
  • tetracyclines
  • macrolides
  • aminoglycosides
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6
Q

Efflux pumps is a mechanism of antibiotic resistance to what antibiotics?

A
  • fluoroquinolones
  • aminoglycosides
  • tetracyclines
  • beta-lactams
  • macrolides
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7
Q

Immunity and bypass is a mechanism of antibiotic resistance to what antibiotics?

A
  • tetracyclines
  • trimethoprim
  • sulfonamides
  • vancomycin
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8
Q

Target modification is a mechanism of antibiotic resistance to what antibiotics?

A
  • fluoroquinolones
  • fiamycins
  • vancomycin
  • penicillins
  • macrolides
  • aminoglycosides
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9
Q

Enzyme inactivation is a mechanism of antibiotic resistance to what antibiotics?

A
  • beta-lactams
  • aminoglycosides
  • macrolides
  • rifamycins
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10
Q

What are the core elements of antimicrobial stewardship programs?

A
  • commitment
  • action/accountability
  • pharmacy expertise
  • education
  • surveillance/tracking
  • reporting
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