Igboin Flashcards

1
Q

Quorum sensing can trigger…

A

biofilm formation because it is necessary to initiate ExoP production

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2
Q

Spirochetes cause…. and …

A

syphillis and lyme disease

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3
Q

treponema pallidum causes… and there is limited knowledge of virulence factors because difficult to culture and lack of animal model

A

syphillis

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4
Q

3 stages of syphillis

A

primary secondary and tertiary

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5
Q

in the … stage of syphillis, WBCs battle spirochetes at site of inoculation forming a syphiitic chancre

A

primary

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6
Q

…% of people go on to stage 2 of syphillis

A

50

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7
Q

septic shock causes… which is called hemodynamic derangement/ MODS(shock phase)

A

high CO and low BP

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8
Q

effect of IL1 and TNFa on blood vessels

A
  • vasodilation
  • low bp
  • vascular leakage/edema
  • bleeding and clots
  • ROS/tissue damage
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9
Q

tx for sepsis

A

high O2
IV fluids
vasopressors
antibiotics

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10
Q

B. fragilis is the predominant species in intra abdominal abscesses because it evades…. tolerates the initial…. of the peritoneal cavity and thrives once…

A
  • phagocytosis
  • oxygenated environment
  • environment becomes anaerobic
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11
Q

intra abdominal infections typically result in … diseases

A

biphasic (acute inflammation, localized abcesses)

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12
Q

bacteriodes are gram…. and are strict… which cant grow in O2 but can tolerate short exposure

A

negative

anaerobes

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