Daniels Flashcards
streptococcus pneumonia is gram… and is the main cause of community acquired pneumonia worldwide
positive cocci
4 characteristics of Streptococcus pneumonia
- diplococci
- aerotolerant anaerobe
- non-spore forming
- encapsulated
Streptococcus pneumonia has a …catalsae test, has …. on blood agar and has … susceptibility
positive
alpha hemolysis (green)
optochin
Carriers of streptococcus pneumonia and transmission
carriers-people- young children are major reservoir
transmission- respiratory secretions/hands
4 stages of pathogenesis of streptococcus pneumonia
- Alveoli fill with fluid
- Early consolidation phase-pus
- Late consolidation phase-affected tissue is solid
- Recovery- macrophage phagocytose
3 antibiotics for tx of streptococcus pneumonia
- penicillin and other beta lactams
- macrocodes
- fluoroquinolone
Vaccines of streptococcus pneumonia are comprised of…. from multiple strains
polysaccharide antigens (capsular)
Legionella pneumophila is a gram… rod
negative pleomorphic (can be large or small)
Legionella pneumophila is a…. aerobe
obligate
Legionella pneumophila comes from…. it is a parasite of…
- contaminated water
- protozoa
Legionella pneumophila is…. tolerant
thermotolerant and can withstand temps above 46 degrees C
What is the therapy for legionella ?
antimicrobial drugs with good intracellular penetration- macrocodes, fluoroquinolone, tetracyclines
…. are not effective for legionella because they do not achieve therapeutic concentrations in the macrophages
Penicillins
The genus staphylococcus is gram… and is non-.. and non-… and is predominately….anaerobes
- positive cocci
- non-motile
- non-spore forming
- facultative anaerobes
Methicillin susceptible S. aureus (MSSA) has … different PBPs
5
PBP 1,2,3 are essential
PBP 3’ and 4