Daniels Flashcards

1
Q

streptococcus pneumonia is gram… and is the main cause of community acquired pneumonia worldwide

A

positive cocci

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2
Q

4 characteristics of Streptococcus pneumonia

A
  1. diplococci
  2. aerotolerant anaerobe
  3. non-spore forming
  4. encapsulated
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3
Q

Streptococcus pneumonia has a …catalsae test, has …. on blood agar and has … susceptibility

A

positive
alpha hemolysis (green)
optochin

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4
Q

Carriers of streptococcus pneumonia and transmission

A

carriers-people- young children are major reservoir

transmission- respiratory secretions/hands

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5
Q

4 stages of pathogenesis of streptococcus pneumonia

A
  1. Alveoli fill with fluid
  2. Early consolidation phase-pus
  3. Late consolidation phase-affected tissue is solid
  4. Recovery- macrophage phagocytose
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6
Q

3 antibiotics for tx of streptococcus pneumonia

A
  1. penicillin and other beta lactams
  2. macrocodes
  3. fluoroquinolone
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7
Q

Vaccines of streptococcus pneumonia are comprised of…. from multiple strains

A

polysaccharide antigens (capsular)

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8
Q

Legionella pneumophila is a gram… rod

A

negative pleomorphic (can be large or small)

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9
Q

Legionella pneumophila is a…. aerobe

A

obligate

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10
Q

Legionella pneumophila comes from…. it is a parasite of…

A
  • contaminated water

- protozoa

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11
Q

Legionella pneumophila is…. tolerant

A

thermotolerant and can withstand temps above 46 degrees C

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12
Q

What is the therapy for legionella ?

A

antimicrobial drugs with good intracellular penetration- macrocodes, fluoroquinolone, tetracyclines

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13
Q

…. are not effective for legionella because they do not achieve therapeutic concentrations in the macrophages

A

Penicillins

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14
Q

The genus staphylococcus is gram… and is non-.. and non-… and is predominately….anaerobes

A
  • positive cocci
  • non-motile
  • non-spore forming
  • facultative anaerobes
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15
Q

Methicillin susceptible S. aureus (MSSA) has … different PBPs

A

5
PBP 1,2,3 are essential
PBP 3’ and 4

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16
Q

Methicillin resistant S. aureus (MRSA) and …. in addition to the 5 PBPs that MSSA have

A

PBP2a

17
Q

Transpeptidases and transglycosylases (…) make the crosslinks in peptidoglycan

A

Penicillin Binding Proteins

18
Q

Staphylococcal food poisoning is caused be a toxin formed in…

A

contaminated unrefrigerated food

19
Q

Staphylococcal food poisoning is not an infection but rather… clinical signs onset is usually…

A
  • an intoxication

- 4 hours post digestion

20
Q

Many strains of S. aureus secrete

A

enterotoxins (A,B,C,D,E)