Idiopathic pulmonary fibrosis Flashcards
what type of disease is idiopathic pulmonary fibrosis
interstitial lung disease(also most common type of it)
describe what idiopathic pulmonary fibrosis is
chronic, progressive, fibrosis of lung parenchyma of uknown cause
describe the symptoms of idiopathic pulmonary fibrosis
progressive dry cough, exertional dyspnoea, weight loss, fatigue
describe the signs on examination of idiopathic pulmonary fibrosis
clubbing, cyanosis, bilateral fine end-respiratory crepitations
describe the risk factors for developing idiopathic pulmonary fibrosis
increasing age, male, cigarette smoking, family history
what are the 4 C’s of idiopathic pulmonary fibrosis
cough, clubbing, cyanosis, crepitations
describe what would be seen on a CXR for idiopathic pulmonary fibrosis
bilateral lower zone reticulo-nodular shadows and reduced lung volume
what spirometry pattern is produced by idiopathic pulmonary fibrosis
restrictive
describe what would be seen on an HRCT of an idiopathic pulmonary fibrosis(IPF) patient
early phase = ground glass appearance
late phase = honey combing changes
when would a lung biopsy or blood tests be relevant for an idiopathic pulmonary fibrosis(IPF) patient
lung biopsy = if HRCT not diagnostic
blood tests = to rule out other causes
what drugs can be used to treat IPF
anti-fibronytic drugs, slow fibrosis not reverse it
example = pirfenidone or nintedanib
when would O2 or lung transplantation be relevant treatments for IPF patients
O2 = if hypoxic
lung transplant = if young patient
what would a major complication of IPF be
respiratory failure
what is the median survival of IPF patients from diagnosis
4 years
