ID Congenital infections

Question 1

Infant evaluation for congenital infections for

Answer 1

All babies

1. SGA (especially symmetric)
2. high risk maternal history
3. congenital defects

Question 2

Usual evaluations include

Answer 2

1. virus isolation studies (nasopharynx, throat, urine, blood, csf)
2. Specific IgM and IgG
3. Quantitative whole IgM

Question 3

congenital infection

Answer 3

CMV, Rubella, Hep B, Hep C, Herpes Simplex, Varicella Zoster, HIV, Parvo, Entero

– Toxoplasma Gondii, Treponema Pallidum

Question 4

Microcephaly, periventricular leukomalacia, cystic calcifications, IUGR, SNHL, Chorioretinitis, HSM

Answer 4

Congenital CMV

Question 5

Deafness, Catracts, IUGR, retinopathy/micropthalmia CHD (PDA, PAS, myocarditis) blue berry muffin skin rash

Answer 5

Congenital Rubella
Dx Culture- nasopharynx, urine, catracts, CSF
IgM or Persistent high IgG