AI immunology

Question 1

Approximate half life on IgG in circulation?

Answer 1

20-25 days

Question 2

Best test for T cell deficiency?

Answer 2

CD4 count

Question 3

Best test to diff. X linked agammaglobulinemia from transient hypogammaglobulinemia?

Answer 3

B cell enumeration

Question 4

What other immunodeficiency must be excluded in selective IgA deficiency?

Answer 4

IgG2 deficiency

Question 5

Immunodeficiency with elevated alpha-!-fetoprotein level?

Answer 5

Ataxia Telangiectasia

Question 6

MC cause of persistent vomiting in CGD patient?

Answer 6

Gastrointestinal Granuloma

Question 7

Test to screen newborns for SCID?

Answer 7

TRECs (T-cell receptor excision circles)

Question 8

Immunodeficiency present in all 12 month old infants?

Answer 8

Selective Antibody Deficiency

Question 9

Which IgG subclass contains most of the polysaccharide antibodies?

Answer 9

IgG2

Question 10

Immunodeficiency with lower IQ learning difficulties

Answer 10

DeGeorge Syndrome

Question 11

Wiskott-aldrich

Answer 11

small platelets

Question 12

Intact antibody responses to protein but not to polysaccharide antigens seen with

Answer 12

Selective Antibody Deficiency

Question 13

Proteins that lack IgA

Answer 13

also lack secretory IgA

Question 14

Kids with pure T cell def. mostly present with

Answer 14

Thrush or PCP