ID Flashcards
What test is done to diagnose syphillitic chancre?
RPR/VDRL blood test
What does a urinary NAAT test look for?
Urethral gonorrhoea and chlamydia
What antibiotic should be prescribed in the event of an animal bite?
Co-amoxiclav
How does an Aspergilloma form?
A mass like fungal ball (mycetoma) colonises an existing lung cavity e.g. 2ary to TB, lung cancer, cystic fibrosis or emphysema
What is the commonest causative agent of malaria?
Plasmodium falciparum
What are the features of falciparum malaria?
Fever HSM Diarrhoea Jaundice Anaemia Thrombocytopenia
What is the transmission risk following needle stick injury of:
HepB
HepC
HIV
HepB - 20-30%
HepC - 0.5-2%
HIV - 0.3%
What should be offered after an initial negative HIV test result in an asymptomatic patient?
Offer repeat test at 12 weeks
How is HIV diagnosed?
HIV antibodies and p24 antigen test
Which bacterial infection its associated with erythema multiform?
Mycoplasma pneumonia
What age group does mycoplasma pneumonia typically affect?
Younger patients
What are the classical features of mycoplasma pneumonia?
Long prodrome with insidious onset
Followed by dry cough
Bilateral consolidation
What are the complications of mycoplasma pneumonia?
Haemolytic anaemia Erythema multiform/nodosum Meningoencephalitis Pericarditis Acute glomerulonephritis
What is the management of mycoplasma pneumonia?
Doxy or a macrolide
What is the incubation period of ebola virus?
2-21 days
What is the first line management of early Lyme disease?
Oral doxy for 14-21 days
What rash is seen in Lyme disease?
Erythema migrans
What are the presenting features of Lyme disease?
Early erythema migrans with systemic features
Cardio - HB, myocarditis
Neuro - CN7 palsy, meningitis
What organism causes bloody diarrhoea and hepatic abscesses?
Entamoeba histolytica
What is the presentation of cutaneous Leishmaniasis?
Crusted ulcerative lesions at the site of the bite
What is the presentation of visceral leishmaniasis?
Fevers sweats rigors
Massive HSM
Grey skin - kala azar
What is the management of acute simple cystitis in a man?
7 days PO Trimethoprim/Nitrofurantoin
Which antibiotic causes a disulfaram like reaction when mixed with alcohol?
Metronidazole
Which Strep causes tonsillitis/pharyngitis?
Pyogenes
What should be given to patients with injuries high risk for Tetanus infection?
Tetanus vaccine booster AND tetanus IM Ig
Gastroenteritis with short incubation period and vomiting?
Staph a
Heat are the features of enteric typhoid fever/
Systemic upset initially
Relative bradycardia
Abdo pain + constipation
Rose spots on trunk
Which class of antibiotics can cause black hairy tongue?
Tetracyclines
What are the adverse effects of tetracyclines?
Discolouration of the teeth
Photosensitivity
Angioedema
Black hairy tongue
What might cause a falsely negative Mantoux test?
Immunosuppression (sarcoid, steroids, AIDs, lymphoma)
What are the features of Legionella pneumonia?
Flu like prodrome Dry cough Confusion Recent foreign travel Hyponatraemia Pleural effusion
What is the diagnosis and management of Legionella pneumonia?
Dx - urinary antigens
Rx - Macrolide
Which causes of gastroenteritis have the longest incubation period?
Giardiasis and amoebiasis - >7 days
What are the live attenuated vaccines and when should they be avoided?
BCG MMR Oral polio Yellow fever Oral typhoid
In immunosuppressed patients
What organisms cause the following LP picture?
High protein
Normal glucose
Lots of mononuclear cells
HSV (Virus)
How does Kaposi’s sarcoma present in children?
Usually no rash
Often only with generalised lymphadenopathy and enlarged tonsils
What is the first line management of syphilis?
IM BenPen
What is the Jarisch-Herxheimer reaction?
Seen sometimes following syphillis treatment
Presents with fever rash tachycardia but no signs of anaphylaxis.
Manage solely with antipyretics
What are clue cells seeing?
Bacterial vaginosis?
What is the management of bacterial vaginosis?
PO metronidazole
How does diphtheria present?
Sore throat with grey ‘diphtheric membrane’ covering to tonsils
Cervical lymphadenopathy
Cranial nerve palsies
Heart block
What happens to TPHA and VDRL results post syphilis management?
TPHA - remains positive
VDRL - goes negative
What antibiotic is used for gonorrhoea?
IM Cef
What antibiotic is used for extensive otitis extern?
Flucloxacillin
What is the antibiotic management of PID?
Doxy + Met + Def
Which chest infection causes reactivation of herpes simplex virus?
S. pneumonia
Which antibiotics are commonly used to treats MRSA?
Vancomycin
Teicoplanin
Linezolid
What antibiotic is used fro Legionella?
Clarithromycin
What infection are sewage workers at risk of, why, and how does it present?
Leptospirosis
Transmitted via rat urine
Fever Flu Renal failure Jaundice Subconjunctival haemorrhage
How long is HIV PEP?
4 weeks
What is the management of Toxoplasma gondii?
6 months of sulfadiazine and pyrimethamine
What are the causes of painful and painless penile ulcers?
Painless - Syphilis, Lymphogranuloma Venereum, Donovanosis
Painful - Behcets, HSV, Chancroid
What causes a gram negative diplococci meningitis?
Neisseria meningitidis
Which pneumonia causes immune mediated neurological disease?
Mycoplasma pneumonia
Which antibiotic should not be given to patients on methotrexate?
Trimethoprim
Which vaccinations are offered routinely to pregnant women in the UK?
Influenza and pertussis
Fevers on alternating days?
Malaria
What agent might cause chronic opportunistic infection in immunosuppressed patients such as diabetics?
Pseudomonas
Which virus is associated with nasopharyngeal cancer?
EBV
What effect can trimethoprim have on the kidneys?
Can cause tubular dysfunction ->Hyperkalaemia and raised Cr
When should HAART be started?
At the time of diagnosis
What infection is common in renal transplant patients, and does it affect the lungs?
CMV - and yes, CMV pneumonitis
What lung infection famously causes desaturations on exercise?
PCP
What is the management of severe and non severe falciparum malaria, and non-falciparum malaria?
Severe - IV artesunate
Non-severe - Oral artesunate
non-falciparum - Chloroquine
What is the management of asymptomatic bacteruria in pregant women?
Amoxicillin
Which antimalarial is taken weekly and should be avoided in patients with depression?
Mefloquine
What is the incubation period of yellow fever?
2-14 day incubation period
What causes Chagas’ disease?
Trypanosome cruzi
Chagas’ disease features?
Myocarditis -> DCM
Megaoesophagus and megagolon