ICP6: Enamel homeostasis & the development of caries Flashcards

1
Q

Give 3 examples of tooth mineral loss by mechanical wear

A
  • Attrition (Grinding)
  • Abfraction (Acid+Chewing)
  • Abrasion
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2
Q

Define primary caries

A

Lesions on URESTORED surfaces

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3
Q

Define secondary caries

A

Lesions adjacent to fillings

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4
Q

Define residual caries

A

Demineralised tissue left behind BEFORE a filling is placed

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5
Q

Define active caries

A

Caries that is considered to be progressive

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6
Q

Define arrested caries

A

Caries that is no longer progressing

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7
Q

What is the white spot lesion?

A

First sign visible by naked eye, usually visible with strong white light

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8
Q

What is a brown spot lesion?

A

Usually an inactive white spot lesion discoloured by the uptake of dye

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9
Q

What is rampant caries?

A

Multiple active carious lesions in the same patient

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10
Q

What is hidden caries?

A

Caries that are usually in dentine and only detectable by radiography

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11
Q

Why do the earliest visible lesions appear as chalky white spots?

A

As micropores appear in the enamel surface which scatter light to give off a white appearance

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12
Q

Explain subsurface demineralisation

A

Acid from the bacteria leach past tooth surface and start demineralising the sub surface to eventually erode away at the enamel surface

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13
Q

What happens to the Ca2+ concentration in saliva when pH of the mouth drops to 4?

Why does this change occur?

A
  • Vastly increases

- To protect enamel surfaces

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14
Q

How are calcium levels in the saliva so rapidly increased during a cariogenic attack?

A

At normal pH binding salivary proteins hold onto Ca2+

Acidic pH the proteins undergo changes to allow the release of these Ca2+ molecules

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15
Q

Name 4 salivary proteins related to tissue maintenance

A
  • Proline-rich proteins
  • Histidine-rich proteins
  • Cysteine-rich proteins
  • Tyroseine-rich proteins
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16
Q

What could cause xerostomia? 5

A
  • Autoimmune Disease
  • H&N Radiotherapy
  • Salivary gland disease
  • Medication
  • Aplasia of salivary glands
17
Q

What is iatrogenic Xerostomia?

A

When drugs cause Xerostomia

18
Q

Explain the changes to the Stephan Curve for a xerostomic patient

A

pH Levels will rise back to 7 at a much slower rate

19
Q

What is the modern day approach to cariology?

A
  • Minimally invasive
  • Therapeutic rather than surgical
  • Treatment of Caries and Erosion with drugs
    based on Salivary Proteins
  • Molecular Dentistry