ICP3: Dental Plaque Flashcards

1
Q

What are 4 of the general properties of biofilm?

A
  • Protection (e.g. moisture, predators)
  • Slow growth rate
  • Get their physical characteristics from surface
  • The variation of biofilm leads to their metabolic interactions
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2
Q

Define Dental Plaque

A

A complex microbial community on a tooth surface, embedded in a matrix of polymers of bacterial and salivary origin (BIOFILM)

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3
Q

Define biofilm

A

Biofilms are a collective of one or more types of microorganisms that can grow on many different surfaces

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4
Q

How are the properties of microorganisms growing in microfilm different to ones growing from planktonic growth? 2

A
  • Microfilm grows slower

- Microfilm much more resistant to antimicrobial agents

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5
Q

Give 5 examples of synergistic interactions between organisms in a biofilm

A
  • Enzyme sharing
  • Food Chains
  • Co- Adhesion
  • Cell-to-cell signalling
  • Gene transfer
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6
Q

Give 6 examples of antagonistic interactions between organisms in a biofilm

A
  • Bacteriocin production
  • H202 production
  • Organic acid production
  • Bacteriophage release
  • Competition for nutrients
  • Predation
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7
Q

Name 5 different types of dental plaque

A
  • Fissure plaque
  • Approximal plaque
  • Gingival crevice plaque
  • Denture Plaque
  • Calculus
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8
Q

What are the 5 steps of the development of dental plaque

A
  1. Acquired enamel pellicle is deposited on clean tooth surface about 1µm thick
  2. Pioneer species of bacteria will adhere to the acquired pellicle
  3. Pioneering species multiply and form a confluent layer
  4. Accumulated bacterial growth leads to a decrease in oxygen tension which cultures anaerobic bacteria
  5. Plaque maturity
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9
Q

After brushing your teeth how long does it take for the acquired enamel pellicle to form?

A

2 Hours

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10
Q

What5 things is the acquired enamel pellicle composed of?

A
  • Proteins
  • Lipids
  • Glycroproteins
  • Saliva
  • Gingival Crevicular fluid
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11
Q

What 4 components of the enamel pellicle are bacteria derived?

A
  • Glycosyl Transferase
  • Glucans
  • Fructans
  • Bacterial cell fragments
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12
Q

What 5 components of the enamel pellicle are host derived?

A
  • Acidic, proline-rich proteins
  • Amylase
  • Lysozyme
  • Albumin
  • Immunoglobulins
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13
Q

What are the interactions that attract pioneer bacteria to the pellicle?

A

Van der Waals

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14
Q

What are the interactions that repel pioneer bacteria to the pellicle?

A

Electrostatic repulsion between negatively charged bacterial cell and pellicle surface

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15
Q

Explain the molecular interactions between bacteria and pellicle

A

Bacteriums have adhesive molecules that are complementary to the pellicle surface receptors

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16
Q

During the multiplication stage of the pioneer species, co-aggregation occurs, what is this?

A

Cell-to-cell interactions leading to distinctly different bacterial species becoming predetermined ‘partners’ in forming plaque

17
Q

Mature plaque is a _______ community

A

Climax community

18
Q

Are there any benefits of dental plaque for the host?

A

Small amounts can help exclude exogenous organisms

19
Q

How can dental plaque help in the exclusion of exogenous organisms from entering the mouth? 3

A
  • Competition for adhesion receptor sites
  • Competition for nutrients and co-factors
  • Production of inhibitory substances, e.g. acids, H2O2
20
Q

What is calculus?

A

Calcified dental plaque

21
Q

What 3 things is calculus composed of?

A
  • Mineral Deposits
  • Proteins
  • Carbohydrates
22
Q

Where is the most predominant supra gingival location for calculus?

A

Near salivary ducts