IC16 Flashcards
1
Q
Pharm tx for BPSD
A
SSRI (depression/anxiety) e.g. citalopram
or
Antipsychotics (agitation/aggression)
2
Q
When is pharm tx for BPSD considered
A
When there is immediate risk of harm to pt/ others OR pt is severely distressed
3
Q
5 cognitive domains
A
- Learning & memory
- Executive fn
- Perceptual- motor or social
- Complex attention
- Language
4
Q
1st line of tx for BPSD
A
Non-pharm strategies
5
Q
BPSD - early vs late sx
A
Early - depression, anxiety;
Late - agitation/ aggression
6
Q
Medications that may cause BPSD
A
- anticholinergics e.g. antihistamine, TCA
- anticonvulsants
- systemic corticosteroids
- meds w sedative ppty e.g. opioids, benzodiazepines, zopiclone
7
Q
Meds to treat AD
A
- AChE inhibitors e.g. donepezil (for all stages of AD)
- Memantine (mod-severe AD)
8
Q
Memantine: Class
A
Non-competitive NMDA receptor antagonist
9
Q
Memantine: adverse effects
A
- confusion
- constipation
- dizziness
- headache
10
Q
Memantine: Caution
A
Caution in seizure, CVD, severe renal/ hepatic impairment
11
Q
Donepezil: dosing
A
5mg OD initially x 6 weeks, incr to 10mg OD (usual target dose), then 23mg OD
12
Q
Donepezil: Caution or C/I
A
C/I: bradycardia
Caution in seizure, PUD
13
Q
Donepezil: adverse effects
A
- insomnia, vivid dreams
- loss of appetite
- N/V
