IC1 - Anatomy (CNS) Flashcards
What are the brain hemispheres separated by?
Longitudinal Fissure
What are the four lobes in the brain?
Frontal
Parietal
Temporal
Occipital
Where is the frontal lobe located?
Anterior to central sulcus
Superior to lateral fissure
Where is the parietal lobe located?
Posterior to central sulcus
Superior to lateral fissure
Where is the temporal lobe located?
Inferior to lateral fissure
Where is the occipital lobe located?
Posterior to parietal and temporal lobes
Where is the pons located?
Inferior to midbrain and superior to medulla oblongata
Where is the cerebellum?
Posterior to pons (hindbrain) and medulla oblongata
What does the cerebellum consists of?
Midline portion and two hemisphere
Neurons can ____ or _____ impulse.
Generate/ Conduct
Neurons are ______.
Excitable
Glial cells are _____.
non-conducting
A neuron is made up of ______, ______and ______.
dendrites, cell body, axons
Axons conduct impulses ____ from the cell body
away
What is not found in the axonal cytoplasm?
Ribosomes, RER, Golgi
What does the fast component in axon transport?
Cytoplasmic proteins, macromolecules
What does the slow component in axon transport?
Cytoskeletal components
Which part of the neuron conducts impulses towards the cell body?
Dendrites
What do dendrites not contain?
Golgi apparatus
What does presynaptic membrane contains?
Voltage-gated Ca2+ channels
Where is the presynaptic membrane located?
Presynaptic axon terminal
Describe what happens when there is an action potential at the axon terminal
- Ca2+ channel opens and cytosolic Ca2+ increases.
- Exocytosis of neurotransmitter into synaptic cleft.
What happens at the excitatory synapse?
- Neurotransmitter bind
- Na+ channel open
- Postsynaptic membrane depolarize
- Action potential in postsynaptic cell
What happens at the inhibitory synapse?
- Neurotransmitter bind
- K+ and Cl- channel open
- Postsynaptic membrane hyperpolarize
- No action potential in postsynaptic cell
What are the three glial cells?
Astrocytes, Oligodendrocytes, microglia
What are the functions of astroctyes?
- Structural support, scar formation
- Regulate intracellular composition and entry of substances
- Metabolize neurotransmitter
- Mediate exchange of nutrients and metabolites between blood and neurons
_____ astrocyte is located in the white matter while the _____ astrocyte is located in the grey matter.
Fibrous, Protoplasmic
Where is the oligodendrocytes mostly located?
White matter
What is the function of oligodendrocytes?
Produce myelin sheath
Oligodendrocytes in the grey matter function as ______ cells.
Satellite
Microglia is known as the ______ as it becomes mobile after CNS injury.
brain macrophages
What are the three connective tissues elements found in PNS?
Epineurium, Perineurium and Endoneurium
Where is the Schwann cells located?
Endoneurium
Oligodendrocytes in CNS myelinate _____ axons while Schwann cells myelinate ______ axons.
Several, Single
What are the two components of peripheral ganglion?
Satellite cells and connective tissue element
Name the two arteries that supply blood to the brain.
Carotid and vertebral
Name the 3 main place which the vertebral artery supply blood to
Spinal cord, medulla oblongata, cerebellum
The vertebral arteries merge at the midline to form the ________.
Basilar artery
Name the 3 main places which the basilar artery supply blood to
Pons, Cerebellum, inner ear
The basilar artery split and divide into two _______ ________ arteries.
posterior cerebral
Which parts of the brain does the posterior cerebral artery supplies?
Midbrain, medial (occipital lobe), base of the temporal and occipital lobes
The internal carotid artery is situated within ________.
Cavernous sinus
The internal carotid divides into ______ artery and _______ artery
Anterior cerebral, middle cerebral
The anterior cerebral artery supplies the ___ surface of the hemisphere.
medial
The middle cerebral artery supplies the ___ surface of the hemisphere.
lateral
The Circle of Willis is important as it provides _____ circulation.
collateral (in event that one side is occluded slowly)
The circle of Willis is frequent for _____.
aneurysms
Where does the blood from brain drains into?
Venous sinuses and then internal jugular vein
Blood from superficial part of superior aspect drains into ______.
superior sagittal sinus
Blood from inferior part drains into ______.
transverse sinus and superficial middle cerebral vein
The superficial middle cerebral vein drains into the _____.
Cavernous sinus
Where does the blood from centre of brain drains?
Deep cerebral veins and then venous sinus
What is the functions of CSF?
- Absorb shock waves from falls/ blows
- Remove metabolites from brain
The _____ produces CSF.
choroid plexus
Describe the flow of CSF to brain and spinal cord
Lateral ventricle to 3rd ventricle to 4th ventricle (via cerebral aqueduct)
What absorbs the CSF into superior sagittal sinus?
Arachnoid granulations