Ibuprofen PO

Question 1

Ibuprofen Indications

Answer 1

• Mild to moderate pain
• Moderate to severe pain in conjunction with other medicines

Question 2

Ibuprofen Contraindications

Answer 2

1. Known severe allergy
2. Pregnancy
   3.The presence of sepsis, dehydration, shock or clinically significant bleeding. As it can worsen renal impairment and increase the risk of bleeding
3. Known worsening of bronchospasm with NDAIDs.

Question 3

Ibuprofen Cautions

Answer 3

1. Has taken within the last four hours
2. Abdominal pain, particularly if unwell or vomiting
3. Age greater than or equal to 75 years, particularly if frail

Question 4

Ibuprofen Dose Adults

Answer 4

600 mg for adults weighing greater than 80kg

400 mg for adults weighing 80kg or less

Question 5

Ibuprofen Dose Children

Answer 5

See the paediatric drug dose tables for a child

Question 6

Ibuprofen Route and Formulation

Answer 6

Per oral (PO), usually comes in 200mg tablets

Question 7

Ibuprofen Mechanism of Action

Answer 7

• Is a non-steroidal anti-inflammatory drug (NSAIDs)
• Inhibits the activity of the enzyme prostaglandin synthetase, reducing prostaglandin production and causing a reduction in inflammation, pain and fever.

Question 8

Ibuprofen Common Adverse Effects

Answer 8

• Renal impairment
• Increased bleeding
• Can cause Indigestion, gastrointestinal ulceration and bleeding with chronic administration