Ibuprofen Flashcards
1
Q
Indicators for use
A
Mild pain
Moderate to severe pain in addition of other drugs/medicines
2
Q
Contraindications of use
A
Severe allergy
3rd trimester of pregnancy
3
Q
Cautions of use
A
Taken within last 4 hours Abdominal pain ( unwell / vomiting ) Aged 75 or older Dehydration or shock Known renal impairment Known bleeding Clinically significant bleeding Bronchospasm worsening with NSAIDS Taking warfarin Pregnancy
4
Q
MOA ( mechanism of action )
A
Ibuprofen is a NSAID this is predominately used in treating pain
Inhibits prostaglandin synthetase and prostaglandin production resulting in reduction in pain, inflammation and fever
5
Q
Route and dose
A
PO ( per oral )
<80kg 400mg
>80kg 600mg
For paeds consult drug chart
6
Q
Side effects
A
Increased bleeding
Renal impairment
Long term effects
Gastrointestinal bleeding and ulceration
Displaces warfarin
7
Q
Drug life span
A
Onset 30-60mins
Duration 4-6 hours
