IBS

Question 1

What are the main types of IBS?

Answer 1

Constipation-predominant
Diarrhea-predominant
Mixed IBS (alternating)

Question 2

What is the prevalence of IBS in the US?

Answer 2

10-15%

1 of top 10 visits to PCP

Question 3

Rome III Criteria

Answer 3

Recurrent abdominal pain atleast 3 days/month in the last 3 months with 2 of the following

1. Releived by defecation
2. Onset associated with change in stool frequency
3. Onset associated with change in stool form

Question 4

Red Flags of IBS

Answer 4

Symptom onset after age 50
Fam Hx of IBD, Celiac Sprue, or colorectal cancer
Nocturnal diarrhea
**GI Bleeding or iron-deficiency anemia
**Weight loss
**Low Sensitivity, good specificity for organic dz

Question 5

Drugs for Diarrhea

Answer 5

Loperamide
Cholestyramine resin
Alosetron

Question 6

Drugs for Constipation

Answer 6

Psyllium husk
Methylcellulos
Calcium polycarbophil
Lactulose Syrup
70%sorbitol
Polyethylene Glycol
Lubiprostone
Magnesium Hydroxide

Question 7

Drugs for Abdominal Pain

Answer 7

Smooth muscle relaxant
Tricyclic antidepressants
Selective Serotonin Reuptake Inhibitors

Question 8

What is the hallmark of IBS?

Answer 8

Visceral hypersensitivity