IBS Flashcards

1
Q

Chronic and debilitating functional gastrointestinal disorder

A

IBS

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2
Q

What does IBS have an absence of?

A

Red flag symptoms

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3
Q

What is IBS usually relieved by?

A

Defecation

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4
Q

What are the 4 red flag symptoms?

A
  1. Loss of appetite
  2. Rectal bleeding
  3. Fistulas
  4. Strictures
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5
Q

What are the 3 main mechanisms associated with IBS?

A
  1. Altered gut reactivity
  2. Hypersensitive gut with enhanced visceral perception of pain
  3. Dysregulation of the brain-gut axis
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6
Q

Serotonin levels are ______ in constipation

A

Reduced

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7
Q

Serotonin levels are _______ in Diarrhea

A

Increased

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8
Q

True or False: IBS is a severely under-diagnosed syndrome

A

True

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9
Q

Patients experience a reduction in what aspect of life?

A

Work productivity

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10
Q

What is needed to diagnose IBS?

A

Recurrent abdominal pain at least 2 DAYS per week on average over 3 months

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11
Q

For IBS diagnosis, what things need to be associated with it?

A
  1. Pain related to defecation
  2. Change in frequency of stool
  3. Change in form of stool
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12
Q

What must you rule out to diagnose IBS? 3

A
  1. Drug induced diarrhea
  2. Constipation
  3. GI upset
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13
Q

What are the 8 red flag symptoms that aren’t associated with IBS?

A
  1. 50 years or older without colon Ca screening
  2. Recent change in bowel habit
  3. Evidence of GI bleed
  4. Nocturnal pain or passage of stool
  5. Unintentional weight loss
  6. Iron deficiency anemia
  7. Family history of colon cancer or IBD
  8. Potential drug induced
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14
Q

What 5 things can cause drug induced diarrhea?

A
  1. Antibiotics
  2. Caffeine
  3. Colchicine
  4. Sorbitol containing products
  5. Laxatives
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15
Q

What 4 things can cause drug induced constipation?

A
  1. Anticholinergic agents
  2. Aluminum antacids
  3. Opioid analgesics
  4. Anti-diarrheal agents
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16
Q

What 5 drugs can cause drug induced abdominal discomfort?

A
  1. Iron
  2. Corticosteroids
  3. Antibiotics
  4. Bisphosphonates
  5. NSAIDs
17
Q

What are 4 non pharmacological managements for IBS?

A
  1. Dietary manipulation
  2. Fiber
  3. Peppermint oil
  4. Psychological therapies
18
Q

What diet shows the most evidence to help with IBS?

A

FODMAP

19
Q

What 2 things are recommended as part of initial management for IBS?

A
  1. Dietary fiber
  2. Psyllium
20
Q

What can insoluble fiber cause?

A

Bloating

21
Q

What is insoluable fiber not recommended for?

A

IBS-D

22
Q

What is the MOA for peppermint oil?

A

Relaxes smooth muscle and attenuation of visceral hypersensitivity and pain sensation

23
Q

What formulation of peppermint oil is the best?

A

Coated capsule