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GI--Wk 5 > IBD Clinical Lecture > Flashcards

IBD Clinical Lecture Flashcards

1
Q

Basic

UC vs CD

A

UC: confluent mucosal lesion (only in colon)
CD: transmural skip lesions (can be in sm intestine)

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2
Q

Colectomy in UC vs CD

A

UC: curative
CD: helps with Sx, further Tx required

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3
Q

When does fistula formation occur

UC/CD

A

CD more often

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4
Q

Serum tests
Crohn’s
Ulcerative Colitis

A

Chrohn’s: ASCA +

UC: pANCA +

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5
Q

pANCA +

A

Ulcerative Colitis

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6
Q

ASCA +

A

Crohn’s

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7
Q

Erythema nodosum
appearance
association

A

looks like mild bruising an anterior surface of leg

UC and CD

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8
Q

Pyoderma nodosum
appearance
association

A

central ulcer w/ ring of erythema

UC and CD

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9
Q

Galbladder manifestation of UC

A

primary sclerosing cholangitis

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10
Q

Primary sclerosing cholangitis association

A

UC

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11
Q

Gallstones in IBD

pathology

A

loss of functional ileum

decreased mile salt reuptake

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12
Q

Renal stones in IBD

pathology

A

extra fat lost in stool
Ca2+ lost with fat in stool
Ca2+ normally binds oxalate and keeps in lumen
excess oxalate absorbed in gut
oxalate excreted in kidney
excess oxalate in kidney creates calcium oxalate stones

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13
Q

Ocular manifestation of IBD

A

uveitis

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14
Q

MS manifestation of IBD in young people

A

akylosing spondylitis

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15
Q

Complications of UC

A

toxic megacolon
hypercoagulability
1˚ sclerosing cholangitis

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16
Q

Complications of CD

A

abscess
obstruction
hypercoagulability

17
Q

Random colon Bx during routine colonoscopy in IBD

why do they do that?

A

looking for dysplasia
adenocarcinoma of colon does not follow
adenoma -> adenocarcinoma sequence in IBD
if dysplasia found, colectomy is warranted

18
Q

Ideal IBD Tx in pregnancy

A

keep using Tx that has been working

avoid steroids if possible in 3rd trimester

19
Q

Complications of biologic therapy

A

TNF-α inhibitors
infections (mycobacteria)
malignancy (also re-emergence of previous)
demyelinating disease

20
Q

Dysplasia or cancer on screening colonoscopy

Refusing medical treatment

A

indications of colectomy

21
Q

Prednisone is not

A

maintenance therapy

GI--Wk 5 (14 decks)

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