Clinical Colon Cancer Lecture Flashcards
1
Q
Chemo indicated in what stages of colon cancer
A
III and IV
II depending on invasion
2
Q
Serum CEA
A
used to follow cancer progression
test at diagnosis
3
Q
How many nodes should be sampled in colon cancer
A
at least 12
4
Q
What are high-risk stage II tumors
A
T4 type
invasive
5
Q
Tis T1 T2 T3 T4
A
tumor penetration depth Tis: in situ, only in mucosa T1: submucosa invasion T2: muscularis propria invasion T3: through muscularis propria or subserosa T4: other organs
6
Q
N0
N1
N2
A
node staging
N0: none
N1: 1-3 regional nodes
N2: 4+ regional nodes positive
7
Q
M0
M1
A
metastasis staging
M0: no mets
M1: distant mets
8
Q
Standard Tx of all colon cancer
chemo
A
5-FU
leucovorin
9
Q
Special chemo for stage III colon cancer
A
oxaliplatin
for some reason better outcomes
10
Q
In colonoscopies it’s most important to make it to this structure
A
visualize ileocecal area
11
Q
COX-2 inhibitors
A
for FAP
12
Q
ASA
A
prevent adenoma
13
Q
Cetuximab or panitumumab
use
A
in KRAS wildtype only
