Ibd

Question 1

Definition of IBD

Answer 1

“A chronic idiopathic intestinal inflammation including Ulcerative Colitis

Question 2

Common risk factors for IBD

Answer 2

“Geographical factors

Question 3

Ulcerative Colitis (UC) pattern of inflammation

Answer 3

“Diffuse

Question 4

Most common site involvement in UC

Answer 4

“Rectum and recto-sigmoid (40-50%).”

Question 5

Pancolitis percentage in UC

Answer 5

“Occurs in 20% of cases.”

Question 6

Genetic factor difference between UC and Crohn’s

Answer 6

“No specific gene in UC

Question 7

Smoking and UC

Answer 7

“Smokers are less likely to develop UC

Question 8

Appendectomy and UC risk

Answer 8

“Appendectomy at a young age reduces the likelihood of developing UC.”

Question 9

Common symptoms of UC

Answer 9

“Bloody diarrhea

Question 10

Common complications of UC

Answer 10

“Severe bleeding (1%)

Question 11

Key serologic markers in UC

Answer 11

“p-ANCA (50-80% of cases) and ASCA (less sensitivity in indeterminate colitis).”

Question 12

Endoscopic findings in mild UC

Answer 12

“Redness

Question 13

Endoscopic findings in moderate UC

Answer 13

“Granularity

Question 14

Endoscopic findings in severe UC

Answer 14

“Severe ulcerations with spontaneous bleeding.”

Question 15

Imaging findings in UC

Answer 15

“Colonic dilation in toxic megacolon

Question 16

Indications for surgery in UC

Answer 16

“Severe hemorrhage

Question 17

Characteristic feature of Crohn’s disease

Answer 17

“Transmural inflammation with skip lesions.”

Question 18

Most common site of Crohn’s disease

Answer 18

“Terminal ileum and cecum (40-50%).”

Question 19

Rectal involvement in Crohn’s disease

Answer 19

“Typically spared.”

Question 20

Endoscopic findings in Crohn’s disease

Answer 20

“Cobblestone appearance

Question 21

Characteristic histological finding in Crohn’s disease

Answer 21

“Non-caseating granulomas (found in 60% of surgical specimens).”

Question 22

Common clinical presentation of Crohn’s disease

Answer 22

“Colicky RLQ pain

Question 23

Extra-intestinal manifestations of Crohn’s

Answer 23

“Arthropathy

Question 24

Nutritional deficiencies in Crohn’s disease

Answer 24

“Vitamin B12 deficiency

Question 25

Common complications of Crohn’s disease

Answer 25

"Fistulas

Question 26

Gold standard for Crohn’s disease diagnosis

Answer 26

"Colonoscopy with biopsy."

Question 27

Characteristic imaging findings in Crohn’s disease

Answer 27

"Skip lesions

Question 28

Role of fecal calprotectin in IBD

Answer 28

"Useful non-invasive marker to distinguish IBD from IBS."

Question 29

Mainstay treatment for mild IBD

Answer 29

"5-Aminosalicylic acid (5-ASA) like sulfasalazine or mesalamine."

Question 30

Role of corticosteroids in IBD treatment

Answer 30

"Used for moderate to severe disease

Question 31

Immunosuppressants used in IBD

Answer 31

"Azathioprine

Question 32

Biologic therapy for IBD

Answer 32

"TNF-alpha inhibitors like Infliximab."

Question 33

Antibiotics used in Crohn’s disease

Answer 33

"Ciprofloxacin and Metronidazole."

Question 34

Surgical indications in Crohn’s disease

Answer 34

"Severe complications like strictures

Question 35

Main difference between Crohn’s and UC in terms of surgical management

Answer 35

"Surgery is curative in UC but not in Crohn’s disease."

Question 36

Which IBD subtype is more associated with fistulas?

Answer 36

"Crohn’s disease."

Question 37

Which IBD subtype has a higher risk of colorectal cancer?

Answer 37

"Ulcerative colitis."

Question 38

IBD treatment approach for perianal Crohn’s disease

Answer 38

"Combination of biologics

Question 39

Which IBD subtype is more likely to present with toxic megacolon?

Answer 39

"Ulcerative colitis."

Question 40

Role of enteral nutrition in Crohn’s disease

Answer 40

"Can be effective in inducing remission

Question 41

Main diagnostic tool for differentiating UC and Crohn’s

Answer 41

"Colonoscopy with biopsy."

Question 42

Common surgery for UC

Answer 42

"Total proctocolectomy with ileal pouch-anal anastomosis (IPAA)."

Question 43

Which IBD subtype has a continuous pattern of inflammation?

Answer 43

"Ulcerative colitis."

Question 44

What are crypt abscesses associated with?

Answer 44

"Ulcerative colitis."

Question 45

Characteristic endoscopic feature of Crohn’s disease

Answer 45

"Cobblestone mucosa with deep ulcerations."

Question 46

First-line therapy for mild to moderate Crohn’s disease

Answer 46

"Oral 5-ASA (Mesalamine or Sulfasalazine)."

Question 47

Most common site of extra-intestinal manifestations in IBD

Answer 47

"Joints (Reactive arthropathy)."

Question 48

Recommended colonoscopy frequency for patients with long-standing UC

Answer 48

"Every 1-2 years."

Question 49

Role of fecal lactoferrin in IBD

Answer 49

"Biomarker for intestinal inflammation

Question 50

Management of fulminant UC

Answer 50

"IV steroids