IBD Flashcards

1
Q

Which drugs are used in (IBD) inflammatory bowel disease

A
  1. Aminosalicylates
  2. Glucocorticoids
  3. immunomodulators
  4. biological response modifiers
  5. antibiotics
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2
Q

Name Aminosalicylates

A
  1. Sulphasalazine 
  2. Mesalamine
  3. Olsalazine
  4. Balsalazide
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3
Q

Name glucocorticoids used in IBD

A
  1. Prednisolone
  2. methylprednisolone
  3. Hydrocortisone (cortisol)
  4. budesonide
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4
Q

Name immuno modulator‘s used in IBD

A
  1. Azathioprine
  2. 6- mercaptopurine
  3. Methotrexate
  4. Cyclosporine 
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5
Q

Name biological response modifiers used in IBD

A
  1. Infliximab
  2. Adalimumab
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6
Q

Name antibiotics used in IBD

A
  1. Metronidazole
  2. ciprofloxacin
  3. clarithromycin
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7
Q

What is the mechanism of action of sulphasalazine

A

5-ASA act locally by inhibiting the production of inflammatory mediators

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8
Q

What are the side effects of sulphasalazine

A
  1. Nausea, vomiting and headache
  2. skin rashes, fever
  3. hepatitis
  4. Pancreatitis
  5. pneumatitis
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9
Q

Which drugs are used in Crohn’s disease

A
  1. Aminosalicylates
  2. Antibiotics
  3. biological response Modifiers 
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10
Q

Name groups of drugs used to treat moderate ulcerative colitis

A
  1. Aminosalicylates
  2. Biological response modifiers
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