Hypoxia And Cyanosis Flashcards

0
Q

Hypoxia induced increase in expression of key proteins is governed by

A

HIF1

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1
Q

Atp production inadequate to mert energy reqts, cell membrane depolarization leads to uncontrolled ca influx… Leading to

A

Cell swelling and cell death

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2
Q

Causes impaired judgment, motor incoordination and clinical picture resembling acute acohol intox

A

Acute hypoxia

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3
Q

Characterized by headache secondary to cerebral vasodilation…

A

High altitude illness

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4
Q

Manifested by severe headache and papilledema and coma

A

HIgh altitude cerebal edema

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5
Q

Cyanosis present since birth or infancy

A

Congenital heart disease

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6
Q

How to differentiate central from peripheral cyanosis?

A

Gentle warming of cyanotic extrrmity abolish peripheral not central

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7
Q

Peripheral cyanosis is not associated with?

A

Clubbing

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8
Q

Clubbing with respiratory diseases is associated with

A

Hypertrophic osteoarthripathy

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9
Q

Florid skin characteristic

A

Polycythemia vera

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10
Q

Cherry colored flush

A

CO Hb

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11
Q

Detectable Fall of o2 sat in dark skinned

A

75%

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12
Q

Cyanosis becomes apparent when concentration of reduced hemoglobin in capillary exceeds..

A

4 g/dl

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13
Q

Cyanosis in altitude ascent of

A

4000m 13000ft

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14
Q

Secondary polycythemia is present and clubbing

A

Chronic central cyanosis

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15
Q

Digital clubbing not present in these rare conditions

A

Met HB and Sulf HB

16
Q

Most common cause of respiratory hupoxia

A

V/q mismatch

17
Q

Condition wherein intrapulmonleft to right shunting is the mechanism

A

Atelectasis

18
Q

In CO poisoning dissociation curve is shifted to

A

Left

19
Q

pao2 is normal but tissue and venous po2 are reduced as a conqequence of reduced tissue perfusion and greater tissue oxygen extraction

A

Circulatory hypoxia

20
Q

Conditions for circ hypoxia

A

Shock

Heart failurr

21
Q

Tissues are unable to utilize oxygen and results to venous blood having high oxygen tension

A

Histotoxic hypoxia

22
Q

Important mechanism for chronic hypoxia

A

Increase in hb concentration and #rbcs

23
Q

Define by ft:
High altitude illness
Chronic mountain sickness

A

13000 ft

Gt 13000 ft