Hypothalamus and Pituitary Gland Flashcards

1
Q

What type if tissue is hypothalamus

A

Neural

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2
Q

How does it connect to pituitary

A

Infandibulum
Neural to PP (hormone situated in hypothalamus and stored in axons in PP which is extension of neural tissue)
Endocrine connection to AP

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3
Q

Where is pituitary situated

A

Sphenoid bone

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4
Q

What can hormones be

A

Trophic

Non-trhopic

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5
Q

What are trophic hormones

A

Govern release of another hormone

Neurohormone goes to AP and govern release of another hormone

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6
Q

What are non-trophic hormones

A

Released into blood for action

e.g Neurone hormones produced in hypothalamus travel to PP via axons

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7
Q

What are all hormones released by hypothalamus and PP

A

Neurohormone

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8
Q

What are all hormones released by AP

A

Endocrine

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9
Q

What 5 releasing hormones does hypothalamus release

A
Thyrotrophin releasing hormone
Corticotrophin releasing hormone
Growth hormone releasing hormone
Gonadotrophin releasing hormone
Prolactin releasing hormone
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10
Q

What 2 inhibiting hormones does hypothalamus release

A

Growth hormone inhibiting hormone (somatostatin)

Prolactin inhibiting hormone (dopamine)

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11
Q

What type of hormones are they

A

All peptide except dopamine which is an AMINE

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12
Q

Action of thyrotrophin releasing hormone

A

Release of thyroid stimulating hormone from AP

Travel to thyroid gland to release thyroid hormone

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13
Q

Action of corticotrophin releasing hormone

A

Release of corticotrophin from AP

Goes to adrenal cortex for cortisol release

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14
Q

Action of growth hormone releasing hormone

A

Release of growth hormone from AP

Goes to liver for IGF-1 release OR direct tissue metabolism

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15
Q

Another name for growth hormone

A

Somatotrophin

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16
Q

Action of gonadotrophin releasing hormone

A

Goes to gonads for sex hormone release

17
Q

Action of prolactin releasing hormone / dopamine

A

Goes to mammilary glands and stimulates prolactin release for lactation

18
Q

What hormones does PP secrete

A

Vasopressin (ADH)

Oxytocin

19
Q

Action of ADH

A

Triggered by increased osmolality or decreased plasma volume
Acts on collecting duct to increase water reabsorption
Smooth muscle contraction to increase BP

20
Q

Action of oxytocin

A

Triggered by labour or sucking
Uterine contraction
Milk ejection

21
Q

What can cause issues

A

Hyposecretion
Hypersecretion
Hyporesponse - alterations in receptors
Hyperresponse - permissive

22
Q

What type of disorders do you get

A

Primary - disorders in cells that secrete hormone
Secondary - too much or too little trophic hormone from pituitary
Tertiary - hypothalamic (rare)