Hypothalamic and Pituitary Imaging Flashcards
Available imaging modalities
- MRI is only logical thing to order
- Can do a CT if MRI is contraindicated (ex. cardiac pacemaker, nerve root stimulators)
- No ionizing radiation
- Can be performed in any plane
- Measures 3 things only:
- Proton density
- T1 relaxation rate
- T2 relaxation rate
- Contrast only affects T1
T1 and T2: relaxation rate, colors, common bright items

Appearance of hypothalamic-pituitary structures on imaging (1 of 3, non-contrast primary T1)


Appearance of hypothalamic-pituitary structures on imaging (2 of 3, non-contrast primary T1)


Appearance of hypothalamic-pituitary structures on imaging (3 of 3, post-constrast T1)


Normal appearance of pituitary and sella on imaging (T1 weighted)


Normal appearance of pituitary and sella on imaging (T2 weighted)


Radiologic appearance of macroadenoma
- Remodels bone, doesn’t bust through (insidious)
- Dumbbell shape as it squeezes through sella
- Mass effets come from growth –> optic chiasm, cavernous sinuses, can collapse arteries
- Cavernous sinuses are dural folds (difficult to approach by neurosurgery)
- Regardless of size and expansion: still staged as adenoma, not carcinoma until distant metastases present

Radiologic diagnosis?

Hyperplasia of pituitary
Radiologic diagnosis?

Pituitary microadenoma
- Right side of adenohypophysis is enlarged
- Focal decreased enhancement in this region
- T2 signal is low

Radiologic diagnosis?

- Giant pituitary macroadenoma (> 4 cm)
- Invasion of clivus, sphenoid sinus, ethmoid air cells, and nasal vault
Radiologic diagnosis?

Rathke Cleft cyst
Radiologic diagnosis?

Lymphocytic hypophysitis
Radiologic diagnosis?

Craniopharyngioma: adamantinomatous type (2 year old child, most commonly calcified in children)
Radiologic diagnosis?

Craniopharyngioma: papillary type
Radiologic diagnosis?

Meningioma