Hypopituitarism - mx

Question 1

How must hypopituitarism be investigated?

Answer 1

each hormone deficiency must be tested indivisually

Question 2

GH deficiency : Ix

Answer 2

1. IGF - 1 levels

2. GHlevels

Question 3

Gonadotropin deficiency :Ix

Answer 3

1. low FSH and low LSH

2. Low estradiol

Question 4

TSH deficiency :Ix

Answer 4

low T2 and T4

Question 5

ACTH deficiency : Ix

Answer 5

1, low cortisol

2. low serum ACTH

Question 6

Central diabets insipidus : Ix

Answer 6

1. water deprivation - low urine osmolality remains

2. exogenous desmopressin - increase urine osmolality

Question 7

Mx of hypopituitarism

Answer 7

1. Transphenoidal resection of macroadenoma

2. hormone replacement therapy