Hypopituitarism Flashcards

1
Q

What is hypopituitarism?

A

deficiency of one or more pituitary hormones

anterior

FSH
LH
ACTH
TSH

Posterior

Prolactin
Endorphins
GH

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2
Q

What is the definition of hypopituitarism?

A

Hypopituitarism refers to the partial or complete deficiency of one or more pituitary hormones. It may arise as a congenital defect during the development of the pituitary gland or as a result of acquired diseases of the pituitary gland, the parasellar structures, or the hypothalamus.

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3
Q

What are some diagnostic features?

A
presence of risk factors
headaches
failure to thrive or short stature
infertility
cardiovascular events
cold intolerance
weight gain
erectile dysfunction and reduced libido
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4
Q

What investigations should be carried out?

A
serum electrolytes
serum and urine osmolarity
8 a.m. cortisol and adrenocorticotrophic hormone
thyroid function tests
insulin tolerance test
water deprivation and desmopressin response test
MRI pituitary
CT pituitary
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