Hypoparathyroidism Flashcards
1
Q
Features and causes?
A
Features-
Low pth,low serum ca, raised serum phosphate,normal ALP
muscle spasms,fits,stridor,diarrhea
Common in premature infants
Causes-
DiGeorge syndrome (associated with thymic aplasia,defective immunity,cardiac defects,facial abnormalities) in infants
Autoimmune disorder associated sith addisons in older children
Surgical removal or damage to blood supply
2
Q
Pseudoparathyroidism features?
A
End organ resistance due to mutation in a signaling molecule
Features- Low ca high po43- but high or N PTH hormone Short Obesity Subcut nodules Short 4th metacarpals Learning difficulties Cataract Teeth enamel hypoplasia Calcification of basal ganglia (gait like in parkinsons)
3
Q
Whata pseudopseudo hypo parathyroidism?
A
Physical characteristics of pseudo hypothyroidism + ca po43- and pth are normal
